Ecology and metabolism of the beneficial intestinal commensal bacterium Faecalibacterium prausnitzii.

Gut Microbes

INRA; Commensal and Probiotics-Host Interactions Laboratory; UMR 1319 Micalis; Jouy-en-Josas, France; AgroParisTech; UMR1319 Micalis; Jouy-en-Josas, France.

Published: February 2015

Faecalibacterium prausnitzii is a major commensal bacterium, and its prevalence is often decreased in conditions of intestinal dysbiosis. The phylogenic identity of this bacterium was described only recently. It is still poorly characterized, and its specific growth requirements in the human gastrointestinal tract are not known. In this review, we consider F. prausnitzii metabolism, its ecophysiology in both humans and animals, and the effects of drugs and nutrition on its population. We list important questions about this beneficial and ubiquitous commensal bacterium that it would be valuable to answer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063839PMC
http://dx.doi.org/10.4161/gmic.27651DOI Listing

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