AI Article Synopsis
- modENCODE was a five-year project funded by NHGRI from 2007 to 2012, aimed at mapping the function of each base in the genomes of worms and flies.
- The project characterized various genetic features, including modified histones, DNA replication origins, RNA transcripts, and transcription factor binding sites that influence gene expression.
- The article focuses on the Drosophila modENCODE datasets, providing guidance on how to access and utilize them for both genome-wide analyses and studies of individual genes.
Article Abstract
modENCODE was a 5year NHGRI funded project (2007-2012) to map the function of every base in the genomes of worms and flies characterizing positions of modified histones and other chromatin marks, origins of DNA replication, RNA transcripts and the transcription factor binding sites that control gene expression. Here we describe the Drosophila modENCODE datasets and how best to access and use them for genome wide and individual gene studies.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857704 | PMC |
| http://dx.doi.org/10.1016/j.ymeth.2014.03.007 | DOI Listing |
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