Sinensioside A, a new sesquilignan glycoside from Selaginella sinensis.

Aim: To investigate the chemical constituents of Selaginella sinensis (Desv.) Spring.

Methods: Chromatographic separations on Diaion HP-20, silica gel, and Sephadex LH-20 were used. The structures of the isolates were elucidated on the basis of spectroscopic analysis, as well as chemical methods.

Results: Eight compounds were obtained and their structures were identified as sinensioside A (1), syringaresinol-4- O-β-D-glucopyranoside (2), (+)-medioresinol-4-O-β-D-glucopyranoside (3), pinoresinol-4, 4'-di-O-β-D-glucopyranoside (4), quercetin (5), eucomic acid (6), shikimic acid (7), and 2, 3-dihydroamentoflavone (8).

Conclusion: Compound 1 is a new dihydrobenzofuran sesquilignan glycoside from Selaginella sinensis.