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http://dx.doi.org/10.1097/CCM.0000000000000076 | DOI Listing |
Gac Sanit
January 2025
Pharmacy Service, Clínica Universidad de Navarra, Pamplona, Spain; Advisory Committee on the Financing of Pharmaceutical (CAPF), Spain.
This paper describes the reforms recommended by the Advisory Committee on the Financing of Pharmaceuticals (CAPF) for the National Health System (NHS) of Spain from 2019 to 2024 for the drug pricing and reimbursement process, to integrate economic evaluations and improve efficiency and sustainability. The CAPF has proposed a three-phase reform of the economic evaluation (EE) and budget impact analysis (BIA) processes. The first phase involves the mandatory submission of EE and BIA by applicants for new drugs.
View Article and Find Full Text PDFWater Res
January 2025
School of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China; State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong SAR, China. Electronic address:
Flow meters are commonly used in manholes to monitor the flow rate for sewer operation and management. However, the large-scale deployment of flow meters in a sewer system is cost-prohibitive due to their high costs and the need for frequent maintenance. This paper proposes a soft sensor that estimates flow rates based on water level measurements in a manhole.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Nano Lett
January 2025
National Key Laboratory of Uranium Resources Exploration-Mining and Nuclear Remote Sensing, East China University of Technology, Nanchang 330013, China.
Efficient sacrificial-agent-free photosynthesis of HO from air and water represents the greenest, lowest-cost, most real-time avenue for HO production but remains a challenging issue. Here, we show a general and effective approach through a structural design on covalent organic frameworks (COFs) with asymmetric dual-function hybrid linkages for boosting the HO photosynthesis of the COFs. Through such design we can equip a COF with not only a catalytic active center but also a special function for isolating the D-A motif, which consequently endows the COF (CI-COF) built on asymmetric dual-function hybrid linkages with a significantly enhanced efficiency in the generation, transmission, and separation of photogenerated carriers, relative to the COF (II-COF and CC-COF) built on symmetric single-function single linkages.
View Article and Find Full Text PDFACS EST Air
January 2025
Lyles School of Civil & Construction Engineering, Purdue University, West Lafayette, Indiana 47907, United States.
Commercial HVAC systems intended to mitigate indoor air pollution are operated based on standards that exclude aerosols with smaller diameters, such as ultrafine particles (UFPs, D ≤ 100 nm), which dominate a large proportion of indoor and outdoor number-based particle size distributions. UFPs generated from occupant activities or infiltrating from the outdoors can be recirculated and accumulate indoors when they are not successfully filtered by an air handling unit. Monitoring UFPs in real occupied environments is vital to understanding these source and mitigation dynamics, but capturing their rapid transience across multiple locations can be challenging due to high-cost instrumentation.
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