Background: Epicutaneous test made with dust mite antigens.
Objective: Evaluation of the response of the epicutaneous test with Aleuroglyphus ovatus antigen in atopic patients.
Methods: We patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test using Aleuroglyphus ovatus antigen in different concentrations and 48 and 96h reading times among those individuals.
Results: Six patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non-atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well.
Conclusion: Our data suggest a positive relation between Atopy Patch Test positive responses and Aleuroglyphus ovatus antigen concentration, no matter the kind of the atopic clinical expression.
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| http://dx.doi.org/10.1111/jdv.12429 | DOI Listing |
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