Paediatr Child Health
Department of Pediatrics, McGill University, Montreal, Quebec.
Published: January 2014
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938211 | PMC |
http://dx.doi.org/10.1093/pch/19.1.7 | DOI Listing |
Africa, with 18.3% of the world's population, faces a significant research output gap, contributing only 2% of global research despite bearing a substantial disease burden. This discrepancy is partly due to inadequate research infrastructure, limited funding, and a shortage of physician-scientists.
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November 2024
Institute of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.
Inflammatory bowel disease (IBD) is a chronic and recurring lifelong condition, the exact etiology of which remains obscure. However, an increasing corpus of research underscores the pivotal role of cellular signaling pathways in both the instigation and management of intestinal inflammation. , owing to its prodigious offspring, abbreviated life cycle, and the conservation of signaling pathways with mammals, among other advantages, has become a model organism for IBD research.
View Article and Find Full Text PDFHum Reprod Update
December 2024
C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI, USA.
Background: Successful implantation is a critical step for embryo survival. The major losses in natural and assisted human reproduction appeared to occur during the peri-implantation period. Because of ethical constraints, the fascinating maternal-fetal crosstalk during human implantation is difficult to study and thus, the possibility for clinical intervention is still limited.
View Article and Find Full Text PDFPLoS One
December 2024
Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México City, México.
Bacteria employ two-component signal transduction systems (TCS) to sense environmental fluctuations and adjust their cellular functions. The Arc TCS is crucial for facultative anaerobes as it enables adaptation to varying respiratory conditions. The Escherichia coli ArcB detects redox changes through two cysteine amino acid residues within its PAS domain.
View Article and Find Full Text PDFAdv Biochem Eng Biotechnol
November 2024
University of Helsinki, Helsinki, Finland.
Microbes are the third major group of biospheric organisms after plants and animals. They are responsible for many natural circulations, including the rotation of elements. They return organic carbon for plants' use and dissolve minerals into organic cycles.
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