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Triple-negative ectopic breast cancer of the male scrotum: a case report.
Front Oncol
December 2024
Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, China.
Male breast cancer represents only 1% of all breast malignancies, with ectopic breast cancer in men being even rarer and highly prone to diagnostic challenges. Extramammary Paget's disease (EMPD), a rare cutaneous tumor with non-specific clinical symptoms, is susceptible to misdiagnosis. This report discusses the case of an older male patient who presented with a scrotal mass, later identified as ectopic breast invasive adenocarcinoma upon pathological examination post-lesion excision.
View Article and Find Full Text PDFEctopic pregnancy is a gynaecological emergency. While its identification and management are monumental, it also impacts the patient's future fertility. Ectopic pregnancy is one of the leading causes for maternal deaths in the first trimester.
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View Article and Find Full Text PDFTriple pacing spikes on QRST: What is the mechanism?
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A septuagenarian man underwent dual chamber pacemaker (DDDR - Boston Scientific Massachusetts, U.S.) insertion for a complete heart block.
View Article and Find Full Text PDFDirect and indirect modulation of STAT3/CSE/HS axis in triple negative breast cancer by non-coding RNAs: MALAT-1 lncRNA, miR-486-5p and miR-30a-5p.
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Biochemistry Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt. Electronic address:
Recently, our research group reported an upregulated expression profile of cystathionine γ-lyase (CSE) and cystathionine β-synthase (CBS), key enzymes involved in hydrogen sulfide (HS) production, in triple-negative breast cancer (TNBC) patients. However, the regulatory mechanisms underlying such altered expression patterns are not yet fully understood. In this study, we focused on the role of the STAT3/CSE/HS axis and the potential involvement of non-coding RNAs (ncRNAs), including long and short ncRNAs, in modulating this pivotal pathway.
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