New lipid-like nanomaterials are developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles are shown to induce simultaneous gene expression and silencing both in vitro and in vivo.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160381 | PMC |
| http://dx.doi.org/10.1002/adhm.201400054 | DOI Listing |
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