A 94-year-old man presented with painful leg ulcers that were affecting his mobility. No clear history of these ulcers was obtained on admission or during his initial 7 days of admission and there was no examination made of the ulcer by medical staff during this time. On day 8, a clear history was obtained. It was established that this was a rapidly deteriorating and painful ulcer developing within a 2-week period in previously normal skin. On examination, he had an ulcer clinically consistent with pyoderma gangrenosum which had further enlarged since admission with evidence of newly developing lesions on the legs. He was started on oral and topical therapies and the ulcer improved symptomatically and aesthetically. He was discharged a few weeks later and the patient was followed up by the Dermatology department to ensure continued improvement and eventual resolution.
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http://dx.doi.org/10.1136/bcr-2013-203445 | DOI Listing |
Oman Med J
July 2024
Family Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, Oman.
We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anaemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Department of Dermatology, Bharati Vidyapeeth Deemed University Medical College, Pune, Maharashtra, India
Ann Case Rep
December 2024
Neobiosis LLC, UF Sid Martin Innovate Biotechnology Institute, Alachua, FL 32615, USA.
With this short communication, which contains a new case report on diabetic ulcer, we summarize our research progress in treating several complex conditions at a point where currently available treatments were failing to help the affected patients. We review the first case of lower back pain due to severe spondylitis (T12-L1) treated with intravenous injections of a sterile fraction of human purified amniotic fluid (ViX001) obtained from thoroughly screened volunteers at the time of planned c-section at the term of normal pregnancies. Then, we review the first case of recalcitrant diabetic ulcer treated successfully by twice-daily applications of ViX001 directly on the wound and describe another case of diabetic ulcer treated successfully with ViX001.
View Article and Find Full Text PDFImmunol Med
December 2024
Department of Pediatrics, KKR Sapporo Medical Center, Sapporo, Japan.
Pyoderma gangrenosum (PG) is an extremely rare disorder in children. We report a nine-month-old girl with PG who presented with high-grade fever and rapidly progressive ulcers at the site of a Bacillus Calmette-Guérin (BCG) inoculation 2 months after the immunization. Additional small pustules developed on her hand and posterior neck three months after the immunization and rapidly progressed.
View Article and Find Full Text PDFANZ J Surg
December 2024
Breast & Endocrine Surgical Unit, Royal Adelaide Hospital, Port Road, Adelaide, South Australia, 5000, Australia.
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