Purpose Of Review: Nearly 1% of pregnancies are affected by some type of midtrimester oligohydramnios. Evidence is currently accumulating that suggests the better efficacy of the new therapeutic procedures relative to conventional management. This review summarizes the available evidence.
Recent Findings: The prolongation of the period between the diagnosis of oligohydramnios and delivery following amnioinfusion and amniopatch techniques appears to be strongly associated with the gestational age and whether the situation was based on rupture of the membranes or not. Case series reveal that amnioinfusion significantly improves the perinatal outcome and prolongs the pregnancy in severe second-trimester oligohydramnios in both idiopathic cases and those involving rupture of the amniotic membranes [preterm prelabor rupture of the membranes (PPROM)]. There is clear evidence of a lower frequency of perinatal complications and successfully prolonged gestation in iatrogenic PPROM after the amniopatch technique relative to population controls.
Summary: Identification of potentially modifiable risk factors for the successful prolongation of pregnancy complicated with midtrimester oligohydramnios, and previable PPROM is needed for the improvement of treatment strategies and prognosis. Randomized trials are needed to determine whether amniotic fluid-replenishing strategies can improve pregnancy outcomes.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/GCO.0000000000000051 | DOI Listing |
BMC Pregnancy Childbirth
November 2024
Obstetrics & Gynecology department, Whiston Hospital, Prescot, L35 5DR, UK.
Background: Placental mesenchymal dysplasia (PMD) is a rare, benign, placental disorder characterised macroscopically by an enlarged multi-cystic placenta. It is a condition associated with a range of reported clinical outcomes and can be misdiagnosed as a molar or partial molar pregnancy given the similarities in clinical presentation. We present an unusual case of PMD complicated by fetal growth restriction and oligohydramnios in the second trimester.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
December 2024
Department of Pediatrics, Peking University People's Hospital, Beijing, China.
Background: At present, research has not found easily accessible, accurate, and safe clinical biomarkers that can effectively predict the occurrence of infants born small for gestational age (SGA). The aim of this study is to explore the predictive role of maternal placental growth factor (PIGF) levels on the occurrence of SGA infants.
Method: We conducted a matched case-control study on 226 SGA infants and 226 non-SGA infants born in the Department of Obstetrics, Peking University People's Hospital, from January 2021 to December 2022, with regular monitoring of maternal serum PIGF levels in second trimester during pregnancy.
Indian J Hematol Blood Transfus
October 2024
Department of Clinical Haematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
BMC Pregnancy Childbirth
October 2024
Department of Obstetrics and Gynecology, Chumphon Khet Udomsakdi Hospital and Clinical Medical Education Center, Chumphon, Thailand.
J Matern Fetal Neonatal Med
December 2024
Jersey City Medical Center, Rutgers New Jersey Medical School, Newark, NJ, USA.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!