Myricetin-3-O-β-d-glucuronide, a bioactive flavonol glycoside, was synthesized effectively starting from myricetrin in a total yield of 49.2%. The structures of all synthetic compounds were confirmed by (1)H, (13)C NMR, and HR-MS techniques.
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Azole reagents enabled ligation of peptide acyl pyrazoles for chemical protein synthesis.
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