According to the male disadvantage hypothesis male foetuses react more sensitive to maternal stress factors during gestation. In the present study the gender typical impact of maternal prepregnancy overweight and obesity as well as gestational weight gain on newborn somatometrics was tested on basis of births records of 7565 births, which took place in Vienna Austria. Maternal weight status was determined at the beginning of pregnancy according to the WHO recommendations. Newborns were measured immediately after birth. With increasing maternal prepregnancy weight status and increasing gestational weight gain birth weight, birth length and head circumference increased too. Among male newborns however the increase was lower than among female ones. With increasing maternal weight status the prevalence of macrosome newborns increased significantly. Among girls however this increase was significantly higher. Male foetuses seem to react more sensitive to a higher maternal weight status in comparison to girls. These results can be interpreted in sense of the so called male disadvantage hypothesis.
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Inflammopharmacology
December 2024
Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, 5400, Pakistan.
Rheumatoid arthritis is an autoimmune disorder affecting multiple joints and requires lifelong treatment. Present study was designed to formulate Esculin-loaded chitosan nanoparticles (ENPs) and evaluation of its anti-inflammatory and anti-arthritic action. The acute toxicity study of ENPs was also performed.
View Article and Find Full Text PDFBiol Trace Elem Res
December 2024
Department of Biochemistry, Faculty of Pharmacy, University of Sadat City (USC), Menoufia, Egypt.
Metabolic syndrome during menopause can lead to diabetes, cardiovascular problems, and increased mortality rates. Hormone replacement therapy is recommended to manage climacteric complications, but it has serious adverse effects. This study, therefore, investigated the potential of supplementing some minerals, vitamins, and natural products like boric acid, magnesium, vitamin D3, and extra virgin olive oil on metabolic status of menopausal ovariectomized rats.
View Article and Find Full Text PDFPsychol Health Med
December 2024
Department of Nutrition and Dietetics, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey.
This two-phase study aims to develop the Turkish version of the German Eating Behavior Scale (SEV-Tr), and to investigate the potential associations of eating behaviors with nutritional and health status. In the first phase, the original scale was adapted to the Turkish language and its validity and reliability were assessed in 299 healthy individuals aged 19-64 years. In the second phase, the SEV-Tr was retested in a study population of 110 healthy individuals, aged 19-64 years, and the potential associations between the SEV-Tr score, anthropometrical and biochemical measurements, and other eating behaviors assessed by the Three-Factor Eating Questionnaire (TFEQ-Tr21) were examined.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
December 2024
School of Mathematics, Statistics & Computer Science, University of KwaZulu Natal, Durban, South Africa.
Background: In causal analyses, some third factor may distort the relationship between the exposure and the outcome variables under study, which gives spurious results. In this case, treatment groups and control groups that receive and do not receive the exposure are different from one another in some other essential variables, called confounders.
Method: Place of birth was used as exposure variable and age-specific childhood vaccination status was used as outcome variables.
Biomed Eng Online
December 2024
ORTHOREBIRTH Co., Ltd., Yokohama, Japan.
Background: A biodegradable nonwoven fabric that can be used to extract adipose-derived stem cells (ADSCs) from adipose tissue slices was developed, which were cultured rapidly without enzymatic treatment. The extracted and cultured ADSCs remain on the nonwoven fabric and form a thick cell sheet. The aim was to use the thick cell sheet as a treatment by transplanting it into the living body.
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