We report a new class of dipeptide dendritic structures fabricated on the surface of mica via spin casting and the conditions required to achieve them. Both their structure and formation mechanism have been investigated in detail using Atomic Force Microscopy (AFM) at the nanometre scale. Formation of nanotubular structures and their further interaction is shown to be a key step in dendritic structure growth. A possible candidate for the primary building block in the nanotubular structure has been identified. The dendritic structures were found to be stable in ambient conditions for several months, however, they transform into needle-like crystals upon exposure to 100% (relative humidity) humid air.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3fd00065f | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hypoxia-Responsive Covalent Organic Framework Nanoplatform for Breast-Cancer-Targeted Cocktail Immunotherapy via Triple Therapeutic Switch Mechanisms.
Small
January 2025
School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, China.
Covalent organic frameworks (COFs), known for their exceptional in situ encapsulation and precise release capabilities, are emerging as pioneering drug delivery systems. This study introduces a hypoxia-responsive COF designed to encapsulate the chemotherapy drug gambogic acid (GA) in situ. Bimetallic gold-palladium islands were grown on UiO-66-NH (UiO) to form UiO@Au-Pd (UAPi), which were encapsulated with GA through COF membrane formation, resulting in a core-shell structure (UAPiGC).
View Article and Find Full Text PDFSystematic Evaluation of Extracellular Coating Matrix on the Differentiation of Human-Induced Pluripotent Stem Cells to Cortical Neurons.
Int J Mol Sci
December 2024
Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Induced pluripotent stem cell (iPSC)-derived neurons (iNs) have been widely used as models of neurodevelopment and neurodegenerative diseases. Coating cell culture vessels with extracellular matrixes (ECMs) gives structural support and facilitates cell communication and differentiation, ultimately enhances neuronal functions. However, the relevance of different ECMs to the natural environment and their impact on neuronal differentiation have not been fully characterized.
View Article and Find Full Text PDFEvaluation of the Microstructure and Properties of As-Cast Magnesium Alloys with 9% Al and 9% Zn Additions.
Materials (Basel)
December 2024
Faculty of Mechanical Engineering, Czech Technical University in Prague, 16629 Prague, Czech Republic.
The need to reduce energy consumption means that it is necessary to reduce the weight of vehicles. However, a thick wall of massive elements promotes the formation of casting defects, which must be removed by either plastic processing (straightening) or welding methods (surface and internal discontinuities). Basic alloys contain Al and Zn as the main alloying elements.
View Article and Find Full Text PDFUltrastructural Localization of Glutamate Delta Receptor 1 in the Rodent and Primate Lateral Habenula.
J Comp Neurol
January 2025
Graduate Program in Molecular and Systems Pharmacology, Emory University, Atlanta, Georgia, USA.
Glutamate delta receptor 1 (GluD1) is a unique synaptogenic molecule expressed at excitatory and inhibitory synapses. The lateral habenula (LHb), a subcortical structure that regulates negative reward prediction error and major monoaminergic systems, is enriched in GluD1. LHb dysfunction has been implicated in psychiatric disorders such as depression and schizophrenia, both of which are associated with GRID1, the gene that encodes GluD1.
View Article and Find Full Text PDFLocally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma.
Discov Oncol
January 2025
Pathology Department, Salah Azeiz Institute, 1006, Tunis, Tunisia.
Follicular dendritic cell sarcoma (FDCS) is a rare malignancy, often challenging to diagnose due to its nonspecific presentation and resemblance to other neoplasms. This case highlights a locally advanced nasopharyngeal FDCS initially misdiagnosed as a meningioma, underscoring the importance of differential diagnosis in unusual tumor presentations. A 77-year-old patient presented with nasal obstruction for 3 months.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!