Introduction: About 23,000 patients with spasticity voluntarily chose to undergo a multiple myofiberotomy (MMF), which is an alternative technique consisting in sectioning soft tissues in order to relieve restrictions in joint movements. This technique, first employed by Ulzibat (Russia), is performed outside orthodox clinical controls.
Aims: To perform an external evaluation of the effects of MMF on motor functionality and gait.
Patients And Methods: The study was self-controlled and observation-based and was designed to evaluate the changes in functional variables -Gross Motor Function Classification System, E-dimension of the Gross Motor Function Measure (GMFM) and the Functional Mobility Scale- and 32 gait parameters (measured using analytical instruments) in 22 school-children with spastic diplegia (mean age: 9 years and 6 months; Q1-Q3: 7 years and 11 months to 11 years and 6 months) whose parents opted for an MMF (median of observation: 4 months; range: 3-7 months).
Results: The analysis of hierarchical conglomerates used to determine topographic cut patterns in patients revealed that the surgeons applied one of three sets of cuts to each patient. On analysing the three groups of patients, it was observed that one group worsened overall and another underwent a general significant improvement in the E-dimension of the GMFM (difference of median: 4.86%; 95% confidence interval = 0-6.94%) after the MMF. Some of the gait parameters became significantly normalised (left: hip-flexion range, maximum dorsiflexion with support; right: speed, mean pelvic rotation with support and maximum dorsiflexion with support).
Conclusions: These findings do not back up or justify the use of MMF as a therapeutic option to treat spasticity. It has to be stressed that this technique must be avoided outside study protocols. Nevertheless, results do lay an objective base that may justify a clinical trial and long-term observation-based studies.
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Pediatr Cardiol
January 2025
Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.
We sought to evaluate the intracardiac morphology and associated cardiovascular anomalies in patients with double inlet right ventricle (DIRV) on multidetector CT angiography. A retrospective search of our departmental database was conducted from January 2014 to January 2023 to identify patients with a diagnosis of DIRV on CT angiography. The intracardiac anatomy and associated cardiovascular abnormalities were systematically evaluated.
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January 2025
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Background: Knee injuries resulting in purely cartilaginous defects are rare, and controversy remains regarding the reliability of chondral-only fixation.
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Study Design: Systematic review; Level of evidence, 5.
Am J Sports Med
January 2025
Section of Young Adult Hip Surgery, Division of Sports Medicine, Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.
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Pain Ther
January 2025
Department of Medicine, Nephrology Division, University of Verona, Verona, Italy.
Introduction: Pain is one of the most frequently reported symptoms in hemodialyzed (HD) patients, with prevalence rates between 33% and 82%. Risk factors for chronic pain in HD patients are older age, long-lasting dialysis history, several concomitant diseases, malnutrition, and others. However, chronic pain assessment in HD patients is rarely performed by specialists in pain medicine, with relevant consequences in terms of diagnostic and treatment accuracy.
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January 2025
Dentistry Department, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Objective: To compare the treatment of osteoradionecrosis (ORN) using a protocol that incorporates antimicrobial photodynamic therapy with a conventional treatment protocol.
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