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Lancet
January 2025
La Tunisie Médicale, Tunis, Tunisia.
Dig Liver Dis
January 2025
Service d'Hépato-gastroentérologie. CHU Dupuytren. 2, avenue Martin Luther Ling. 87042 Limoges. France; Unité Mixte de Recherche UMR-1248 « Pharmacologie et Transplantation », Faculté de Médecine et de Pharmacie, Université de Limoges. 2, rue du Dr Marcland, 87024 Limoges, France.
Lab Chip
January 2025
Laboratory for Electrical Instrumentation and Embedded Systems, IMTEK - Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Cell cultures, organs-on-chip and microphysiological systems become increasingly relevant as models, , in drug development, disease modelling, toxicology or cancer research. It has been underlined repeatedly that culture conditions and metabolic cues have a strong or even essential influence on the reproducibility and validity of such experiments but are often not appropriately measured or controlled. Here we review microsensor systems for cell metabolism for the continuous measurement of culture conditions in microfluidic and lab-on-chip platforms.
View Article and Find Full Text PDFExpert Rev Neurother
January 2025
Central Clinical School, Faculty of Medicine and Health, University of Sydney.
Introduction: Cognitive impairment in Parkinson's disease (PD) substantially affects patient outcomes, function, and quality of life. PD-related cognitive dysfunction is often heterogeneous in clinical presentation and rates of progression. As cognitive changes occur in many people with PD, it is essential to evaluate cognition, provide education, and implement management strategies for cognitive symptoms.
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