Neurosensitization effects on the state of the ribonucleoprotein particles and chromatin in nuclei of the Vth layer cortical neurons were studied in female rats. Anti-brain antibodies were investigated in their offspring on the 30th and 60th days. On the 60th day the electron-cytochemical changes were found in the nuclei suggesting the deterioration of nucleolar DNA processing and inhibition of nucleolar functional activity. Anti-brain antibodies were also found in the blood. Direct antibodies interference in the function of cellular DNA-RNA-protein-synthetizing system seems plausible.
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