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Galactomannan extracted from seeds of Cassia grandis with 0.1M NaCl, followed by ethanol precipitation, presented a yield of 36 ± 8%. The polysaccharide has a constant mannose/galactose ratio (2.44:1). Methylation analysis, one and two dimensional NMR spectroscopy confirmed that the polysaccharide has a central core composed of 4-linked β-mannose units, with branches of galactose, linked to the carbohydrate core through α(1-6) linkage. The amorphous nature of the galactomannan was confirmed by X-ray diffraction. Rheological characterization exhibited Newtonian plateaus followed by shear-thinning zones characteristic of polymer solutions up to 1.5% (w/v) and above this value the system exhibited yield stress associated with a weak gel. Adjusting stress-strain curves confirmed a 1.6% (w/v) as the galactomannan concentration value for the sol-gel transition. These results indicate that the galactomannan extracted from C. grandis seeds presents rheological characteristics suitable for applications in pharmaceutical, biomedical, cosmetic and food industries.
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http://dx.doi.org/10.1016/j.carbpol.2014.01.010 | DOI Listing |
Int J Biol Macromol
January 2025
Programa de Pós-Graduação em Saúde e Desenvolvimento Socioambiental - Universidade de Pernambuco, Garanhuns, PE, Brasil; Laboratório Multiusuário de Biotecnologia do Sertão Pernambucano (BIOSPE) - Universidade de Pernambuco, Arcoverde, PE, Brasil.
This study aimed to investigate the antitumor activity of galactomannan extracted from Cassia grandis seeds (GCg) against colorectal cancer cells using both experimental and computational approaches. Galactomannan was extracted from C. grandis seeds and prepared into solutions with varying concentrations.
View Article and Find Full Text PDFCarbohydr Polym
January 2025
Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, People's Republic of China. Electronic address:
Obesity is a serious public health challenge worldwide, the present study is aimed to investigate the structural characteristic and anti-obesity effect of a water-soluble galactomannan (PEC) extracted from Eurotium cristatum (E. cristatum). Detailed analysis of the PEC structure showed a weight-average molecular weight of 32,305 Da and a composition of mainly mannose, galactose and small amounts of glucose.
View Article and Find Full Text PDFCarbohydr Polym
January 2025
School of Food Science and Engineering, Hainan University, Haikou 570228, PR China. Electronic address:
Int J Biol Macromol
December 2024
Postgraduate Program in Materials Science and Engineering - PPGCM, Federal University of Piauí, Teresina, PI, Brazil; Research Center on Biodiversity and Biotechnology, Biotec, Parnaíba Delta Federal University, Parnaíba, PI, Brazil. Electronic address:
The continuous increase in bacterial resistance requires the study and development of new biocompatible antibacterial materials. Galactomannan gum was extracted from endosperms of Dimorphandra gardneriana seeds, modified through quaternization reactions (with NaOH/CHPTAC), and evaluated for antimicrobial activity. Four quaternized derivatives were obtained (QG1-QG4).
View Article and Find Full Text PDFCurr Microbiol
September 2024
Departamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil.
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