The review is dedicated to the problem of interaction of human neutrophils with bacterial biofilms that complicate the course of infectious process. Neutrophils being the most important effectors of innate immunity may attack bacterial biofilms causing their rejections and damage of biofilm microbes. Mechanisms of neutrophil-dependent destruction of biofilms are analyzed in the review. Variants of defense of biofilm bacteria from phagocytosis that are used by them for evading neutrophils and consolidation of biofilm structures are discussed.
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