Situational awareness for science funders: information challenges and solutions for funding agencies in the 21st century.

About 25 years ago, one of our colleagues joined the Wellcome Trust, the world's second largest private biomedical funder. At the time, computers and the Internet were not a regular part of everyday work routines. Today, a quarter of a century later, the Wellcome Trust and other forward thinking funders are leading the way in integrating software, systems, and information technology into their funding processes. While not all research funders have been technologically proactive--some have only recently switched to electronic applications and others still operate with largely document-based processes-almost all funders experience some level of difficulty when it comes to translating technological advances into operational efficiencies and strategic insights. Also, although there are exceptions, funders generally do not share notes. That is scary. It is a rich and perhaps troubling irony that even while they invest billions of dollars in groundbreaking research to solve some of the world's greatest challenges, many funders struggle to find effective solutions to what can seem like pedestrian information challenges: