To understand more about final conversations (communication between loved ones from the point of terminal diagnosis until death), 49 children/adolescents provided final conversation advice for other youth and for the dying person. Advice for fellow youth included (a) confirming the relationship with the dying person, (b) remaining positive throughout the death process, and (c) using external support networks. Advice for the dying person included (a) confirming the relationship with the youth, (b) engaging in open, honest communication with youth, and (c) confirming the identities of the youth. The main implication is that youth should be included in the death process.
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http://dx.doi.org/10.1080/07481187.2012.753556 | DOI Listing |
Lancet
January 2025
Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, UK; Imperial College Renal and Transplant Centre, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK. Electronic address:
Background: In the UK, booster COVID-19 vaccinations have been recommended biannually to people considered immune vulnerable. We investigated, at a population level, whether the absence of detectable anti-SARS-CoV-2 spike protein IgG antibody (anti-S Ab) following three or more vaccinations in immunosuppressed individuals was associated with greater risks of infection and severity of infection.
Methods: In this prospective cohort study using UK national disease registers, we recruited participants with solid organ transplants (SOTs), rare autoimmune rheumatic diseases (RAIRDs), and lymphoid malignancies.
Plant Physiol Biochem
January 2025
College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China. Electronic address:
Competition is ubiquitous and an important driver of tree mortality. Non-structural carbohydrates (NSCs, including soluble sugars and starch) and C-N-P stoichiometries are affected by the competitive status of trees and, in turn, physiologically determine tree growth and survival in competition. However, the physiological mechanisms behind tree mortality caused by intraspecific competition remain unclear.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Introduction: Death is universal, yet relatively little is known about how Canadians experience their death. Using novel decedent interview data from the Canadian Longitudinal Study on Aging we describe the prevalence and characteristics of peace with dying among older Canadians.
Methods: We conducted a secondary analysis of decedent interview data from the Canadian Longitudinal Study on Aging.
Biomaterials
January 2025
College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, PR China; Zhejiang-California International Nanosystems Institute, Zhejiang University, Hangzhou, 310058, PR China; Hangzhou Institute of Innovative Medicine, Zhejiang University, Hangzhou, 310058, Zhejiang, PR China.
Nowadays, photodynamic therapy (PDT) offers a non-invasive tumor treatment with high safety profiles and minimal side effects, implying a promising clinical application for patients with malignant tumors. However, the lack of efficacy in metastasis and recurrence still notably limits its application. To solve this problem, one promising strategy is to improve the immune response activated by PDT.
View Article and Find Full Text PDFPLoS Med
January 2025
National Child Mortality Database, Bristol Medical School, St Michael's Hospital, University of Bristol, Bristol, United Kingdom.
Background: During the COVID-19 pandemic children and young people (CYP) mortality in England reduced to the lowest on record, but it is unclear if the mechanisms which facilitated a reduction in mortality had a longer lasting impact, and what impact the pandemic, and its social restrictions, have had on deaths with longer latencies (e.g., malignancies).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!