AI Article Synopsis
- Gonadotropin-secreting pituitary tumors are typically associated with sellar masses and hypogonadism, but cases with active LH secretion and high testosterone levels are rare.
- A 48-year-old male with a large pituitary tumor exhibited both elevated testosterone and gonadotropin levels.
- Surgical removal of the tumor led to normal gonadotropin levels and a decrease in testosterone, confirming that the tumor was producing biologically active LH.
Article Abstract
Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH).
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926319 | PMC |
| http://dx.doi.org/10.1155/2014/194716 | DOI Listing |
Publication Analysis
Top Keywords
elevated testosterone
8
testicular "hyperstimulation"
4
"hyperstimulation" syndrome
4
syndrome case
4
case functional
4
functional gonadotropinoma
4
gonadotropinoma gonadotropins
4
gonadotropins secreting
4
secreting pituitary
4
pituitary tumors
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!