Splenosis is the heterotopic autotransplantation of splenic tissue that usually follows traumatic splenic rupture and splenectomy. Implanted splenic tissue may give rise to a mass or masses in the chest, abdomen, or pelvis which the clinician must distinguish from benign or malignant tumors. A 38-year-old multiparous woman presented for a routine gynecological examination during breast cancer treatment. She had undergone splenectomy following traumatic splenic rupture at the age of 13. Pelvic examination revealed a left adnexal mass. Transvaginal ultrasonography showed a 39×56×40 mm diameter hyperechoic, hypervascular solid tumor on the left ovary. Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. The postoperative histological diagnosis was splenic tissue. Splenosis must be considered in the differential diagnosis of previosly splenectomized patients who present with unexplained masses.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939106 | PMC |
| http://dx.doi.org/10.5152/jtgga.2011.30 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Histological Assessment of Systemic Toxicity Induced by Zinc oxide Nanoparticles and the Prophylactic Potency of Ascorbate in Albino Rats.
J Microsc Ultrastruct
December 2022
Department of Histology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Background: Nanoparticles of zinc oxide (ZnO-NPs) are frequently implemented in cosmetics, additives, and electronic devices. Moreover, their applications extend to water treatment, drug delivery, and cancer therapy. As a result, NP toxicity became an essential subject in biosafety research.
View Article and Find Full Text PDFThe influence of interleukin-27 on metabolic fitness in a murine neonatal model of bacterial sepsis.
Am J Physiol Endocrinol Metab
January 2025
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, 64 Medical Center Drive, Morgantown, WV, 26506, USA.
Human neonates are predisposed to an increased risk of mortality from infection due to fundamental differences in the framework of innate and adaptive immune responses relative to those in the adult population. As one key difference in neonates, an increase in the immunosuppressive cytokine, IL-27, is responsible for poor outcomes in a murine neonatal model of bacterial sepsis. In our model, the absence of IL-27 signaling during infection is associated with improved maintenance of body mass, increased bacterial clearance with reduced systemic inflammation, and decreased mortality rates that correlate to preservation of glucose homeostasis and insulin production.
View Article and Find Full Text PDFThe ethanolic extract of Rhaphidophora peepla prevents inflammation by inhibiting the activation of Syk/AKT/NF-κB and TAK1/MAPK/AP-1.
Phytomedicine
January 2025
Department of Integrative Biotechnology, and Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, Suwon 16419, Republic of Korea; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:
Background: Inflammation is the body's innate reaction to foreign pathogens and serves as a self-regulating mechanism. However, the immune system can mistakenly target the body's own tissues, triggering unnecessary inflammation. For millennia, medicinal plants have been employed for the treatment of diseases.
View Article and Find Full Text PDFPET-CT-based host metabolic (PETMet) features are associated with pathologic response in gastroesophageal adenocarcinoma.
Eur J Surg Oncol
January 2025
Division of Surgical Oncology, Department of Surgery, Northwell Health, New Hyde Park, NY, USA; Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:
Background: F-FDG PET-CT-based host metabolic (PETMet) profiling of non-tumor tissue is a novel approach to incorporate the patient-specific response to cancer into clinical algorithms.
Materials And Methods: A prospectively maintained institutional database of gastroesophageal cancer patients was queried for pretreatment PET-CTs, demographics, and clinicopathologic variables. F-FDG PET avidity was measured in 9 non-tumor tissue types (liver, spleen, 4 muscles, 3 fat locations).
IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis.
BMC Immunol
January 2025
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University School of Medicine, Chungnam National University Hospital, 282 Munhwa-Ro, Jung-Gu, Daejeon, 35015, Republic of Korea.
Background: Interleukin-6 (IL-6) plays a central role in sepsis-induced cytokine storm involving immune hyperactivation and early neutrophil activation. Programmed death protein-1 (PD-1) is associated with sepsis-induced immunosuppression and lymphocyte apoptosis. However, the effects of simultaneous blockade of IL-6 and PD-1 in a murine sepsis model are not well understood.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!