The nature of the interactions among self-propelled agents (SPA), i.e., topological versus metric or a combination of both types, is a relevant open question in the field of self-organization phenomena. We studied the critical behavior of a Vicsek-like system of SPA given by a group of agents moving at constant speed and interacting among themselves under the action of a topological rule: each agent aligns itself with the average direction of its seven nearest neighbors, independent of the distance, under the influence of some noise. Based on both stationary and dynamic measurements, we provide strong evidence that both types of interactions are manifestations of the same phenomenon, which defines a robust universality class. Also, the cluster size distribution evaluated at the critical point shows a power-law behavior, and the exponent corresponding to the topological model is in excellent agreement with that of the metric one, further reinforcing our claim. Furthermore, we found that with topological interactions the average distance of influence between agents undergoes large fluctuations that diverge at the critical noise, thus providing clues about a mechanism that could be implemented by the agents to change their moving strategy.
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http://dx.doi.org/10.1103/PhysRevE.89.012139 | DOI Listing |
ACS Nano
January 2025
Department of Bioengineering, University of Washington, Seattle, Washington 98195-5061, United States.
The recent development of modular universal chimeric antigen receptor (CAR) T-cell platforms that use bifunctional adaptor intermediates to redirect engineered T-cell effector function has greatly expanded the capabilities of adoptive T-cell therapy, enabling safer and more comprehensive cancer treatment. However, universal CAR receptor systems rely on unstable transient recognition of tag-coupled intermediates for T-cell activation, and the array of targeting intermediates has been limited to antibodies and small molecules. Addressing these shortcomings, we engineered universal CAR T-cell receptors that can be covalently modified with synthetic biomaterials by accelerated SpyCatcher003-SpyTag003 chemistry for cancer-cell targeting.
View Article and Find Full Text PDFInt J Nurs Stud Adv
June 2025
Centre of Excellence in Early Intervention and Family Studies, Department of Psychology, University of Copenhagen, Denmark.
Background: Screening for perinatal depression using the Edinburgh Postnatal Depression Scale (EPDS) improves detection and increases health service utilization. However, previous studies with antenatal samples indicate that positive screenings might reflect transient distress that resolves without intervention, raising concerns about over-pathologizing typical postnatal responses and inefficiencies in referral practices. Therefore, distinguishing between transient and enduring depressive symptoms for appropriate referrals to secondary services is crucial, highlighting the need for a refined screening practice.
View Article and Find Full Text PDFSci Rep
January 2025
Whales Initiative, Ocean Wise Conservation Association, Vancouver, BC, Canada.
The expansion of drone-based aerial imagery has facilitated an increase in data obtained from free-ranging marine mammal populations, in particular cetacean species. This non-invasive approach allows for body condition assessments, including nutritional and reproductive health. Yet, existing methods of image analysis are time-consuming and lack the granularity to determine early-stage pregnancies and miscarriage rates.
View Article and Find Full Text PDFLancet Planet Health
January 2025
Chinese Center for Disease Control and Prevention, Beijing, China; Department of Epidemiology, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
Sand and dust storms increasingly threaten global environmental and public health. To date, 150 countries are directly affected, with more than 100 classified as non-dust source regions. With climate change, these storms are expected to become more frequent and severe.
View Article and Find Full Text PDFJ Colloid Interface Sci
January 2025
Key Lab of Organic Optoelectronics & Molecular Engineering, Tsinghua University, Beijing 100084, PR China. Electronic address:
Exploring suitable dual active site and metal-substrate interface effect is essential for designing efficient and robust electrocatalysts across a wide pH range for the hydrogen evolution reaction (HER). Herein, alloyed platinum-ruthenium clusters supported on nanosheet-assembled molybdenum carbide microflowers (PtRu/MoC) are reported as efficient pH-universal electrocatalysts for HER. Due to dual active site and metal-substrate interface effect, the optimized PtRu/MoC electrocatalyst exhibits extremely low overpotentials (η) of 9, 19, and 33 mV to deliver 10 mA cm in 0.
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