A progressively diminishing capacity of eye to visualize for close proximity increasing by age is known as presbyopia which is usually resulted due to loss of elasticity of crystalline lens. A clinical trial was conducted to evaluate the efficacy of coded herbal formulation "ocucure" (Test drug) for the treatment of presbyopia comparing with leutivit (Placebo). One hundred and eleven patients suffering from presbyopia from both groups (Males: 63, mean age: 34±14 and females: 48, mean age: 33±13 year, range: 20-60) were enrolled in the trial and divided in to two groups according to treatment regimens. Ocucure (Test drug) 500mg two tablets and leutivit (Placebo) 250mg tablets twice daily were prescribed for 6-8 weeks. Presbyopia was improved in 17 patients (28.81%) out of 59 patients by the use of ocucure (Test drug), and in 6 patients (11.53%) out of 52 by the use of leutivit (Control drug). Furthermore, there was a significant improvement in presbyopic associated clinical features as compared to leutivit. It is concluded that ocucure possesses a therapeutic value for the improvement of presbyopia and its associated symptoms as compared to leutivit.
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