Objectives: To determine whether feeding type of trophic feeds affect haematological and biochemical markers in the very preterm infant.
Design And Methods: Fifty-six very preterm infants were enrolled in this retrospective study (30 infants were included in the only human milk-fed group and 26 in the formula-fed group). Routine haematological and biochemical variables were collected in both groups on days 1 and 4 of life and fourteen serum markers were measured.
Results: There were no significant differences between the two groups before starting trophic feeds. After starting trophic feeds, sodium and lactate levels were significantly higher in the human milk-fed group compared with those measured in the formula-fed group.
Conclusion: The study demonstrates that supplementation of minimal enteral feeding with human milk does affect biochemical profiles in very preterm infants. Small amounts of enteral feedings of formula and/or human milk may result in different metabolic responses; these differences are reflected by different serum biochemistries.
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http://dx.doi.org/10.1016/j.clinbiochem.2014.02.017 | DOI Listing |
Front Cell Infect Microbiol
December 2024
Data Center, Meizhou People's Hospital, Meizhou Academy of Medical Sciences, Meizhou, China.
Background: Premature infants are at high risk for neonatal respiratory distress syndrome (RDS) and secondary infections. This study aims to investigate the association between immunoinflammatory markers-the systemic immune inflammation index (SII), systemic inflammation response index (SIRI), and neutrophil-to-albumin ratio (NAR)-and the risk of developing RDS in premature infants.
Methods: A total of 2164 premature infants were enrolled in this retrospective study.
Cureus
November 2024
Pediatrics, K S Hegde Medical Academy, Mangaluru, IND.
Antenatal corticosteroids (ACS) are widely used to reduce respiratory distress syndrome (RDS) in preterm neonates, enhancing neonatal outcomes. However, the potential effects of ACS on other aspects of neonatal health, such as cortisol levels and glucose regulation, remain a concern. This study examines whether ACS administration impacts cortisol and glucose homeostasis in preterm infants by analyzing data from 14 selected studies.
View Article and Find Full Text PDFCureus
November 2024
Keep Well, Model of Care, Eastern Health Cluster, Dammam, SAU.
Preterm birth, defined as delivery before 37 weeks of gestation, is a significant contributor to neonatal morbidity and mortality worldwide. Understanding the prevalence of preterm birth is critical to improving neonatal care, informing public health strategies, and supporting health care planning. The objective of this study was to explore the problem of preterm birth in Saudi Arabia by estimating the prevalence of preterm birth over a defined period of time.
View Article and Find Full Text PDFTurk J Med Sci
December 2024
Department of Ophthalmology, Faculty of Medicine, University of Health Sciences, Tepecik Research and Training Hospital, İzmir, Turkiye.
Background/aim: In Türkiye, the recommendations for screening for retinopathy of prematurity (ROP) were updated in 2021. We aimed to present detailed data on the infants included in the screening program according to the new criteria and evaluate whether these changes are of benefit in detecting severe ROP.
Materials And Methods: Our hospital's medical records of infants screened for ROP between July 2019 and July 2021 or between August 2021 and August 2023 were retrospectively examined.
BMJ Paediatr Open
December 2024
Department of Pediatrics, Division Neonatology, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.
Background: The neonatal Sequential Organ Failure Assessment (nSOFA) score is an organ dysfunction score developed for predicting mortality risk in preterm neonates with proven late-onset neonatal sepsis (LONS) and necrotising enterocolitis. However, the utility of the nSOFA score in determining the risk of retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD) or mortality in patients with suspected LONS is unknown.
Methods: We performed a dual-centre retrospective cohort study of preterm (gestational age <32 weeks) neonates suspected of LONS, from 2016 to 2020 at two neonatal intensive care units.
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