In the review of the literature modern data on mechanisms phagocytes protection of periodontium, sold monocytes-macrophage system and neutrophil are resulted. The opportunity of programming of a morphological amd functional phenotype of macrophage is analyzed by change of concentration of whey of blood. Data on functioning in gingival sulcus or periodontal pocket << extracellular neutrophil traps>> are resulted. Opportunities to operate by the nonspecific protective answer of fabrics periodontium on microbic aggression are shown.

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