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Oral lesions associated with Nevirapine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases. | LitMetric

AI Article Synopsis

  • Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe skin reactions often triggered by medications, posing serious health risks.
  • Individuals with HIV, particularly those taking nevirapine (NVP), face a higher risk of developing SJS or TEN.
  • The article discusses nine cases of SJS and one case of TEN in HIV-positive patients experiencing various lesions while on NVP treatment.

Article Abstract

Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely related severe, acute mucocutaneous reactions usually caused by drugs. They are acute life-threatening conditions and cause widespread necrosis of the epithelium. There is persistence of a high risk of SJS or TEN in relation to human immunodeficiency virus (HIV) infection associated with exposure to nevirapine (NVP). In this article, we present nine cases of SJS and one case of TEN in HIV-seropositive individuals who developed cutaneous, oral, ocular and genital lesions while being treated with NVP.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927350PMC
http://dx.doi.org/10.4103/0973-029X.125214DOI Listing

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