A genetic link between cutaneous melanoma and thyroid cancer (TC) has been identified. A high percentage of both melanomas and papillary carcinomas of the thyroid harbors a recurrent mutation (i.e., BRAF(V600E) ) in the BRAF oncogene. Herein, we report the case of a 65-year-old man with papillary TC and cutaneous malignant melanoma metastatic to masseter muscle, both characterized by BRAF mutation. This is one of the rare reports in which a complete molecular characterization has been performed. As the patients with papillary thyroid carcinoma have a higher risk of malignant melanoma and vice versa, continuous monitoring of such patients, with either of these tumors is necessary. Fine-needle aspiration cytology is useful as shown in the present case.

Download full-text PDF

Source
http://dx.doi.org/10.1002/dc.23060DOI Listing

Publication Analysis

Top Keywords

malignant melanoma
12
papillary thyroid
8
thyroid carcinoma
8
fine-needle aspiration
8
aspiration cytology
8
detection brafv600e
4
brafv600e mutation
4
papillary
4
mutation papillary
4
thyroid
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!