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COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients.
Aliment Pharmacol Ther
January 2025
Gastrointestinal and Liver Theme, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, School of Medicine, Queen's Medical Centre, Nottingham, UK.
Background: Colorectal cancer (CRC) is the third most common cancer in the United Kingdom and the second largest cause of cancer death.
Aim: To develop and validate a model using available information at the time of faecal immunochemical testing (FIT) in primary care to improve selection of symptomatic patients for CRC investigations.
Methods: We included all adults (≥ 18 years) referred to Nottingham University Hospitals NHS Trust between 2018 and 2022 with symptoms of suspected CRC who had a FIT.
Incidence of fall-from-height injuries and predictive factors for severity.
J Osteopath Med
January 2025
McAllen Department of Trauma, South Texas Health System, McAllen, TX, USA.
Context: The injuries caused by falls-from-height (FFH) are a significant public health concern. FFH is one of the most common causes of polytrauma. The injuries persist to be significant adverse events and a challenge regarding injury severity assessment to identify patients at high risk upon admission.
View Article and Find Full Text PDFContinuous Polarizability-Based Separation of Lithium Iron Phosphate and Graphite Using a Dielectrophoretic Particle Separator.
Langmuir
January 2025
College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.
The recovery of valuable materials from spent lithium-ion batteries (LIBs) has experienced increasing demand in recent years. Current recycling technologies are typically energy-intensive and are often plagued by high operation costs, low processing efficiency, and environmental pollution concerns. In this study, an efficient and environmentally friendly dielectrophoresis (DEP)-based approach is proposed to separate the main components of "black mass" mixtures from LIBs, specifically lithium iron phosphate (LFP) and graphite, based on their polarizability differences.
View Article and Find Full Text PDFIdentification of diagnostic and therapeutic biomarkers for attention-deficit/hyperactivity disorder.
Kaohsiung J Med Sci
January 2025
Department of Psychiatry, School of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric condition among children and adolescents, often associated with a high risk of psychiatric comorbidities. Currently, ADHD diagnosis relies exclusively on clinical presentation and patient history, underscoring the need for clinically relevant, reliable, and objective biomarkers. Such biomarkers may enable earlier diagnosis and lead to improved treatment outcomes.
View Article and Find Full Text PDFUsing system dynamics modeling approach to strengthen health systems to combat cancer: a systematic literature review.
J Med Econ
January 2025
UNESCO-TWAS, The World Academy of Sciences, Trieste, Italy.
Aim: Dynamic cancer control is a current health system priority, yet methods for achieving it are lacking. This study aims to review the application of system dynamics modeling (SDM) on cancer control and evaluate the research quality.
Methods: Articles were searched in PubMed, Web of Science, and Scopus from the inception of the study to November 15th, 2023.
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