A new bisanthraquinone has been isolated from the stems of Cratoxylum cochinchinense together with vismiaquinone C and 16 known xanthones. Their structures were characterised by using spectroscopic methods. Two of the isolated compounds are modified xanthones (6 and 15) and exhibited strong cytotoxicity against human epidermoid carcinoma (A341: IC50 2.01, 1.78 μg/mL) and human breast cancer cell lines (SKBR3: IC50 1.54, 0.69 μg/mL).
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Polyprenylated xanthones with potential anti-inflammatory and anti-HIV effects from the stems and leaves of (Lour.) Blume.
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Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, P. R. China.
A phytochemical study on the stems and leaves of (Lour.) Blume resulted in the isolation and characterisation of a new polyprenylated xanthone, cratocochinone (), as well as seven known analogues, fuscaxanthone K (), pruniflorone Q (), 1,3,5,8-tetrahy-droxy- 2-(3-methybut-2-enyl)-4-(3,7-dimethylocta-2,6-dienyl) xanthone (), cochinensoxanthone (), cratoxylum-xanthone B (), cochinchinone I () and cochinchinone K (). The chemical structure of was determined by comprehensive spectral analyses.
View Article and Find Full Text PDF[Chemical constituents from stems and leaves of Cratoxylum cochinchinense and their inhibitory effects on proliferation of synoviocytes in vitro].
Zhongguo Zhong Yao Za Zhi
September 2023
Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University Haikou 571127,China Engineering Research Center for Industrialization of Southern Medicinal Plants Resources of Hainan Province, Hainan Normal University Haikou 571127,China Key Laboratory of Southern Medicinal Plants Resources of Haikou City, Hainan Normal University Haikou 571127,China.
Article Synopsis
- - Chemical compounds were extracted and identified from the stems and leaves of *Cratoxylum cochinchinense*, using various chromatography techniques, leading to the isolation of 21 different compounds.
- - Out of these, one compound was a new xanthone, while several others had not been previously identified in the *Cratoxylum* plant; some were newly discovered in *C. cochinchinense*.
- - The isolated compounds were assessed for their anti-rheumatoid arthritis effects, with xanthones 1-15 showing significant inhibition of synoviocyte proliferation, indicating potential therapeutic benefits.
Xanthones with Potential Anti-Inflammatory and Anti-HIV Effects from the Stems and Leaves of .
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Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, China.
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Front Chem
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Division of Applied Life Science (BK21 Four), Institute of Agriculture and Life Science (IALS), Gyeongsang National University, Jinju, Republic of Korea.
The root of has been widely used as Chinese folk medicine to cure fevers, burns, and abdominal complications because it contains various bioactive metabolites such as xanthones, triterpenes, and flavonoids. In this study, we estimated bacterial neuraminidase inhibition with a series of xanthones from . BNA has connected to various biological functions such as pathogenic bacteria infection inflammatory process after infection and biofilm formation.
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Key Laboratory of Research on Pathogenesis of Allergen Provoked Allergic Disease in Liaoning Province, Shenyang Medical College, Shenyang, China.
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