Cholangiocarcinoma: increasing burden of classifications.

Hepatobiliary Surg Nutr

Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino, Rome, Italy; ; Eleonora Lorillard Spencer-Cenci Foundation, Rome, Italy.

Published: October 2013

Cholangiocarcinoma (CCA) is a very heterogeneous cancer from any point of view, including epidemiology, risk factors, morphology, pathology, molecular pathology, modalities of growth and clinical features. Given this heterogeneity, a uniform classification respecting the epidemiologic, pathologic and clinical needs is currently lacking. In this manuscript we discussed the different proposed classifications of CCA in relation with recent advances in pathophysiology and biology of this cancer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924690PMC
http://dx.doi.org/10.3978/j.issn.2304-3881.2013.10.02DOI Listing

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