Objective: The aim of this pilot study was to compare the efficacy of ALA-PDT and red light alone in the treatment of photoaging.
Methods: A total of 14 adults with photoaging skin were recruited. ALA-PDT or red light alone was applied to the forearm extensor. Before and after treatment, the treated sites were examined by dermoscopy, the changes in straum corneum (SC) hydration, transepidermal water loss (TEWL), and the L*a*b* values were measured, and microscopic examination of collagens and elastins was performed.
Results: After ALA-PDT or red light illumination, the appearance of photoaging lesions improved, SC hydration increased and TEWL decreased. These changes in the ALA-PDT group were more obvious than those in the red light group. No significant change was noticed in the L*a*b* values in both groups. The signs of typical solar elastosis damage were improved in both groups.
Conclusions: ALA-PDT showed better skin rejuvenation effect than red light alone.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pdpdt.2014.02.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
New Zealand Early Learning Service Menus Do Not Meet Health New Zealand Guidelines for Providing Healthy Menus and Reducing Food-Related Choking in Children.
Health Promot J Austr
January 2025
School of Sport, Exercise and Nutrition, Massey University, Auckland, New Zealand.
Objective: To assess alignment of food and drinks served to New Zealand (NZ) children in early learning services (ELS) with the Health NZ (formerly known as Ministry of Health) Healthy Food and Drink (HFD) and Reducing Food Related Choking (choking) guidance.
Methods: Menus (271) collected remotely from 148 ELS from November 2020-March 2021 were analysed for their nutritional quality based on a 'traffic light' classification of 'green' (most nutritious), 'amber' (moderately nutritious) and 'red' (least nutritious) based on the guidance.
Results: Overall, 2.
Light Spectral-Ranged Specific Metabolisms of Plant Pigments.
Metabolites
December 2024
Department of Crop Science, College of Agriculture, Life and Environment Sciences, Chungbuk National University, Cheongju 28644, Republic of Korea.
Chlorophyll is the primary pigment responsible for capturing light energy during photosynthesis, while carotenoids assist in light absorption and provide photoprotection by dissipating excess energy. Both pigments are essential for plant growth and development, playing distinct and complementary roles in maintaining photosynthetic efficiency and protecting plants from oxidative stress. Because of their function in photosynthesis and photoprotection, chlorophyll and carotenoid accumulation are strongly associated with light conditions, especially blue and red lights, which play key roles in regulating their metabolisms.
View Article and Find Full Text PDFRed-light mediated formylation of indoles using a helical carbenium ion as a photoredox catalyst.
Chem Commun (Camb)
January 2025
Department of Chemistry, Indian Institute of Technology Ropar (IIT Ropar), Rupnagar, Punjab-140 001, India.
Low-energy photoredox catalysis has gained significant attention in developing organic transformations due to its ability to achieve high penetration depth and minimum health risks. Herein, we disclose a red-light ( = 640 nm)-mediated C-3 formylation of indoles utilizing a helical carbenium ion as a photocatalyst and 2,2-dimethoxy-,-dimethylethanamine as a formylating source. These protocols exhibit a broad substrate scope under mild conditions with efficient scalability for the synthesis of C-3 formylated indoles.
View Article and Find Full Text PDFEnhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model.
Iran J Basic Med Sci
January 2025
Department of Pharmacology, Faculty of Medicine, Maranatha Christian University, Bandung 40164, West Java, Indonesia.
Objectives: Both intrinsic and extrinsic factors cause skin aging. Intrinsic aging is characterized by decreased collagen density, particularly collagen types I (COL1A1) and III (COL3A1), and an increase in the COL1/COL3 ratio. Extrinsic aging, primarily due to ultraviolet light exposure, leads to photoaging, which causes collagen fragmentation and reduced production, leading to skin sagging.
View Article and Find Full Text PDFPhotodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms.
J Nanobiotechnology
January 2025
Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Road, Shanghai, 200011, China.
The escalating hazards posed by bacterial infections underscore the imperative for pioneering advancements in next-generation antibacterial modalities and treatments. Present therapeutic methodologies are frequently impeded by the constraints of insufficient biofilm infiltration and the absence of precision in pathogen-specific targeting. In this current study, we have used chlorin e6 (Ce6), zeolitic imidazolate framework-8 (ZIF-8), polydopamine (PDA), and UBI peptide to formulate an innovative nanosystem meticulously engineered to confront bacterial infections and effectually dismantle biofilm architectures through the concerted mechanism of photodynamic therapy (PDT)/photothermal therapy (PTT) therapies, including in-depth research, especially for oral bacteria and oral biofilm.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!