Background: Pemphigoid gestationis (PG), also known as herpes gestationis, is an uncommon autoimmune blistering disease that almost always occurs in the third trimester of pregnancy. The sudden emergence of the disease, its clinical appearance and the course create great stress on the pregnant woman and the fetus. The disease has been associated with premature delivery and small-for-gestational-age infants. Corticosteroids remain the mainstay of therapy.
Case: A pregnant woman presented with a diffuse blistering and intensely pruritic urticarial plaques that occurred periumbilically and spread to the rest of the body. We report a well-documented case of PG and an overview of the current understanding of the disease.
Conclusion: A multidisciplinary approach for diagnosis, treatment and course of the disease from both dermatologic and gynecologic viewpoints is suggested.
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Article Synopsis
- Pregnancy leads to significant changes in a woman’s skin, particularly on the face and trunk, due to hormonal, mechanical, and immune factors.
- Common skin alterations during this time include hyperpigmentation, stretch marks, and various vascular changes, along with potential issues like skin tags and other specific conditions.
- Understanding these changes is crucial for healthcare providers to offer proper support and management for expectant mothers, improving clinical care and paving the way for future research.
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