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Article Synopsis
  • - Scheie syndrome is a rare, milder form of mucopolysaccharidosis type I, which primarily affects multiple organ systems and is rarely linked to cancer, with only one prior case of associated brain tumors reported almost 30 years ago.
  • - The case presented involves a 10-year-old girl diagnosed with Scheie syndrome, who also developed a brain tumor identified through MRI as a pilocytic astrocytoma, a rare type of brain tumor found in the fourth ventricle.
  • - This situation emphasizes the need for careful evaluation of children with mucopolysaccharidoses for potential brain tumors, particularly when they exhibit signs of increased intracranial pressure, as early detection can prevent serious neurological issues.
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Article Synopsis
  • - Crouzon syndrome is a common type of craniofacial dysostosis, characterized by unusual skull shapes, unique facial features, and protruding eyes.
  • - Dental issues in patients with Crouzon syndrome are often overlooked in medical research, despite potential related neurological problems.
  • - A case study of a four-year-old girl with Crouzon syndrome highlights her symptoms, including a displaced lower jaw and dental abnormalities, confirmed through advanced imaging and genetic testing.
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An uncommon autosomal dominant condition known as Crouzon's syndrome causes abnormalities of the skull and face. It accounts for 4.8% of all cases of craniosynostosis and is by far the most prevalent condition among them.

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