We demonstrate a mid-IR frequency comb centered at 3120 nm with 650-nm (20-THz) bandwidth at a comb-teeth spacing of 500 MHz. The generated comb is based on a compact ring-type synchronously pumped optical parametric oscillator (SPOPO) operating at degeneracy and pumped by a mode-locked Er-doped 1560 nm fiber laser at a repetition rate of 100 MHz. We achieve high-repetition rate by using a fractional-length cavity with a roundtrip length of 60 cm, which is one-fifth of the length dictated by conventional synchronous pumping.
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http://dx.doi.org/10.1364/OL.39.000900 | DOI Listing |
J Biomed Opt
December 2024
University of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Significance: Cellular metabolism is highly dynamic and strongly influenced by its local vascular microenvironment, gaining a systems-level view of cell metabolism is essential in understanding many critical biomedical problems in a broad range of disciplines. However, very few existing metabolic tools can quantify the major metabolic and vascular parameters together in biological tissues with easy access.
Aim: We aim to fill the technical gap by demonstrating a point-of-care, easy-to-use, easy-to-access, rapid, systematic optical spectroscopy platform for metabolic and vascular characterizations on biological models to enable scientific discoveries to translate more efficiently to clinical interventions.
Philos Trans A Math Phys Eng Sci
December 2024
Istituto di Fotonica e Nanotecnologie del CNR, Piazza Leonardo da Vinci 32, Milano 20133, Italy.
This work provides a mathematical derivation of a quasi-stationary (QS) model for multimode parametric down-conversion (PDC), which was presented in Gatti . (Gatti ., .
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Université Paris Cité, CNRS, Laboratoire Matériaux et Phénomènes Quantiques, 75013 Paris, France.
Harnessing high-dimensional entangled states of light presents a frontier for advancing quantum information technologies, from fundamental tests of quantum mechanics to enhanced computation and communication protocols. In this context, the spatial degree of freedom stands out as particularly suited for on-chip integration. But while traditional demonstrations produce and manipulate path-entangled states sequentially with discrete optical elements, continuously coupled nonlinear waveguide systems offer a promising alternative where photons can be generated and interfere along the entire propagation length, unveiling novel capabilities within a reduced footprint.
View Article and Find Full Text PDFAnal Chem
December 2024
Joint Mass Spectrometry Centre/Chair of Analytical Chemistry, University of Rostock, 18059 Rostock, Germany.
To our knowledge, this study presents the first implementation of wavelength-resolved resonance-enhanced multiphoton ionization (REMPI) spectroscopy under atmospheric pressure ionization conditions using a high-resolution mass spectrometric system. Atmospheric pressure laser ionization MS spectroscopic measurements were conducted on over 70 different polycyclic aromatic hydrocarbons (PAHs) and hetero-PAHs (N, S, and O) in standard solutions, as well as three complex PAH-containing samples. The results demonstrate the successful transfer of REMPI spectroscopy from vacuum to atmospheric pressure conditions, maintaining spectral integrity without significant band broadening.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
December 2024
Department of Ophthalmology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 24, Zurich, 8091, Switzerland.
Introduction: Paediatric uveitis is a rare disease. It can affect any segment and have various etiologies, including infectious, autoimmune, and masquerade diseases. The pupose of this study is to analyse and present the demographic data in paediatric uveitis in a Swiss cohort.
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