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Identification of Early and Late Responders to Anti-IL-13 Antibody Tralokinumab in Atopic Dermatitis: A Real-World Japanese Study.
Dermatitis
December 2024
From the Department of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Japan.
Tralokinumab, an anti-IL-13 antibody, is an effective treatment for patients with atopic dermatitis (AD). However, predictive factors for responders to tralokinumab remain unclear in real-world practice. This study aimed to identify predictive factors for early and late responders to tralokinumab treatment.
View Article and Find Full Text PDFThe Beneficial Roles of Seaweed in Atopic Dermatitis.
Mar Drugs
December 2024
Department of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by severe pruritus and recurrent flare-ups, significantly impacting patients' quality of life. Current treatments, such as corticosteroids and immunomodulators, often provide symptomatic relief but can lead to adverse effects with prolonged use. Seaweed, a sustainable and nutrient-dense resource, has emerged as a promising alternative due to its rich bioactive compounds-polysaccharides, phlorotannins, polyphenols, and chlorophyll-that offer anti-inflammatory, antioxidant, and immunomodulatory properties.
View Article and Find Full Text PDFPreparation of Patchouli Oil Microemulsion Gel and Its Topical Application to Ameliorate Atopic Dermatitis in Mice.
Gels
December 2024
School of Pharmacy, Inner Mongolia Medical University, Hohhot 010100, China.
Patchouli oil (PO) is a natural substance famous for its immune-enhancing and anti-inflammatory effects. Atopic dermatitis (AD) is characterized by epidermal gene mutations, skin barrier dysfunction, and immune dysregulation, making patchouli volatile oil a potential candidate for AD treatment. Initially, PO was mixed with ethyl oleate (EO), castor oil ethoxylated ether-40 (EL-40), anhydrous ethanol, and water to form a patchouli oil microemulsion (PO-ME) system.
View Article and Find Full Text PDFThe Role of Diet, Nutrition, and Supplements in Canine Atopic Dermatitis.
Vet Clin North Am Small Anim Pract
December 2024
Pet Dermatology Clinic, 9712 63rd Avenue North, Maple Grove, MN 55369, USA. Electronic address:
This review summarizes studies on diet, nutrition, and supplements in the management of canine atopic dermatitis with focus on the past 10 years (2020-2024). Diet plays a large role in the management of canine atopic dermatitis, especially for patients with a food allergy. There is minimal evidence supporting the use of probiotics, fatty acid supplementation, vitamin E, vitamin D, Zinc, or cannabinoids, although they may be a useful adjunct.
View Article and Find Full Text PDFTransdermal delivery of natural products against atopic dermatitis.
Chin J Nat Med
December 2024
Department of Pharmacy, Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo 315010, China. Electronic address:
Atopic dermatitis (AD) is a chronic inflammatory skin condition. Natural products have gained traction in AD treatment due to their accessibility, low toxicity, and favorable pharmacological properties. However, their application is primarily constrained by poor solubility, instability, and limited permeability.
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