CD103(+) dendritic cells (DCs) must acquire soluble food antigens from the gut lumen to induce oral tolerance. In this issue of Immunity, Mazzini et al. (2014), report that CX3CR1(+) macrophages capture such antigen and transfer it to the DCs by a route involving gap junctions.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.immuni.2014.01.008 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!