Objectives: To present graphical tools for reporting network meta-analysis (NMA) results aiming to increase the accessibility, transparency, interpretability, and acceptability of NMA analyses.
Study Design And Settings: The key components of NMA results were identified based on recommendations by agencies such as the National Institute for Health and Care Excellence (United Kingdom). Three novel graphs were designed to amalgamate the identified components using familiar graphical tools such as the bar, line, or pie charts and adhering to good graphical design principles.
Results: Three key components for presentation of NMA results were identified, namely relative effects and their uncertainty, probability of an intervention being best, and between-study heterogeneity. Two of the three graphs developed present results (for each pairwise comparison of interventions in the network) obtained from both NMA and standard pairwise meta-analysis for easy comparison. They also include options to display the probability best, ranking statistics, heterogeneity, and prediction intervals. The third graph presents rankings of interventions in terms of their effectiveness to enable clinicians to easily identify "top-ranking" interventions.
Conclusions: The graphical tools presented can display results tailored to the research question of interest, and targeted at a whole spectrum of users from the technical analyst to the nontechnical clinician.
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http://dx.doi.org/10.1016/j.jclinepi.2013.11.006 | DOI Listing |
J Knee Surg
January 2025
Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Shijingshan District, Beijing, People's Republic of China.
Single-bundle (SB) and double-bundle (DB) anterior cruciate ligament reconstruction (ACLR) have been compared for years, and long-term outcomes of the two techniques remain inconclusive. We compared the 10-year outcomes of SB and DB reconstruction, in terms of subjective scores, knee stability, graft failure, and osteoarthritis (OA). We searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials for relevant studies, without restrictions on study design, language, or publication date.
View Article and Find Full Text PDFEnviron Microbiol
January 2025
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California, USA.
Ecological assembly-the process of ecological community formation through species introductions-has recently seen exciting theoretical advancements across dynamical, informational, and probabilistic approaches. However, these theories often remain inaccessible to non-theoreticians, and they lack a unifying lens. Here, I introduce the assembly graph as an integrative tool to connect these emerging theories.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
January 2025
Institute of Mathematical Sciences Centre for Health Analytics and Modelling (CHaM), Strathmore University, Nairobi, Kenya.
Background: Measures of diagnostic test accuracy provide evidence of how well a test correctly identifies or rules-out disease. Commonly used diagnostic accuracy measures (DAMs) include sensitivity and specificity, predictive values, likelihood ratios, area under the receiver operator characteristic curve (AUROC), area under precision-recall curves (AUPRC), diagnostic effectiveness (accuracy), disease prevalence, and diagnostic odds ratio (DOR) etc. Most available analysis tools perform accuracy testing for a single diagnostic test using summarized data.
View Article and Find Full Text PDFCureus
January 2025
Edinburgh Medical School, The University of Edinburgh, Edinburgh, GBR.
Over the past few decades, technological advancements have established digital tools as an indispensable pedagogical resource in the realm of modern education. In the field of medical education, there is growing interest in how these digital tools can be effectively integrated to enhance undergraduate surgical education. However, despite their well-documented potential benefits, research specifically investigating the current use of digital technology in undergraduate surgical education remains limited, highlighting a critical gap in the existing literature.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Mathematics and Statistics, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
In applied research, fractional calculus plays an important role for comprehending a wide range of intricate physical phenomena. One of the Klein-Gordon model's peculiar case yields the Phi-four equation. Additionally, throughout the past few decades it has been utilized to explain the kink and anti-kink solitary waveform contacts that occur in biological systems and in the field of nuclear mechanics.
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