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Human papillomavirus-associated diseases. | LitMetric

Human papillomavirus-associated diseases.

Clin Dermatol

Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Gundulićeva 5, 10000 Zagreb, Croatia.

Published: November 2014

AI Article Synopsis

  • HPV is linked to various conditions, including cervical cancer, especially through types 16 and 18, which are commonly found in cancerous tissues.
  • Although HPV can cause other cancers and benign conditions, its impact is less significant compared to cervical cancer.
  • Vaccination is currently the most effective way to prevent HPV-related diseases, while cervical screening helps detect precancerous lesions early.

Article Abstract

The human papillomavirus (HPV) may be associated with various oral, genital, and cutaneous conditions, both benign and malignant. The association between sexually transmitted α-HPV types is the strongest with cervical cancer because almost all such malignancies contain viral DNA, notably HPV types 16 and 18. The contribution of cancer causing HPV types in other anogenital, oral, and oropharyngeal malignancies, plus benign disorders, is lower and with a less significant public health concern. Cervical cytologic screening is a well-established preventive measure that allows early detection and successful treatment of precancerous cervical lesions. In cases of all other HPV-associated disorders, early detection of a precancerous lesion is either difficult or almost impossible. HPV vaccination remains the only preventive measure against most HPV-related diseases.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clindermatol.2013.10.006DOI Listing

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