In order to change the driving mode of ion shutter, simplify the design of ion shutter driving power and improve the resolution of ion mobility spectrometry, a series of resistors were added to achieve asymmetric power supply of ion shutter, and the low voltage part was controlled to realize the function of ion shutter. Two conditions in this mode, the effect of electric field in drift tube and the resolution and signal-to-noise ratio of ion mobility spectrum were analyzed. Aided by SIMION 7.0, the electric field distribution at both sides of ion shutter was simulated and compared. Electric field data of drift tube axis was calculated through the method of numerical solution of Laplace equation. Experiment has proved that: compared with floating ground driving power used in conventional ion mobility spectrometry, the driving mode was low cost, and the design of ion shutter driving power supply was simple, and the resolution of ion mobility spectrometry was enhanced significantly. The method can be used in measurement instrument or experimental device of ion mobility spectrometry.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Ultrahigh Resolving Power Ion Mobility Spectrometry with a Simple Pulser Circuitry.
Anal Chem
December 2024
Department of Chemistry, University of Basel, Klingelbergstrasse 80, Basel 4056, Switzerland.
The pulsing circuitry for high resolving power drift-tube ion-mobility spectrometry is based on three avalanche photodiodes. These are switched on by illumination through optical fibers, which provide electrical insulation of the driver circuitry from the high voltage. The setup was tested with a series of quaternary ammonium ions introduced with an electrospray ion source.
View Article and Find Full Text PDFHigh Resolving Power Electrospray Ionization Ion Mobility Spectrometer Based on Fourier Deconvolution Multiplexing.
Anal Chem
October 2024
College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China.
Article Synopsis
- - The resolving power of drift tube ion mobility spectrometry (IMS) relies on several factors, including drift length, voltage, pulse width of the ion gate, and tube pressure.
- - Electrospray ionization (ESI)-IMS offers high sensitivity for analyzing nonvolatile compounds, necessitating high resolving power to distinguish similar structures effectively.
- - The study explores Fourier deconvolution (FD) multiplexing to enhance resolving power and signal-to-noise ratio, demonstrating that a 5 μs ion gate opening can achieve a resolving power of 170 without extending the drift length, successfully separating structurally similar compounds.
Conservation of the Charge in Signal from Drift Tube Ion Mobility Spectrometers.
Anal Chem
October 2024
Faculty of Advanced Technologies and Chemistry, Military University of Technology, ul. gen. Sylwestra Kaliskiego 2, Warsaw 00-908, Poland.
Quantitative information obtained from drift tube detectors used in ion mobility spectrometry is contained in the area of peaks forming the drift time spectrum. The area of all peaks corresponds to the total charge of ions entering the drift section of the spectrometer. It was found that this charge is not conserved when the ion composition changes.
View Article and Find Full Text PDFA hyper-fast gas chromatograph coupled to an ion mobility spectrometer with high repetition rate and flow-optimized ion source to resolve the short chromatographic peaks.
J Chromatogr A
November 2024
Leibniz Universität Hannover, Institute of Electrical Engineering and Measurement Technology, Department of Sensors and Measurement Technology, Hannover 30167, Germany.
By combining the high selectivity of a gas chromatograph (GC) with the high sensitivity and decent selectivity of an ion mobility spectrometer (IMS), GC-IMS have become increasingly popular in many applications. However, most GC suffer from long analysis times. In contrast, an hyper-fast GC allows for extremely fast analysis in the tens of seconds while reaching comparably high resolution.
View Article and Find Full Text PDFFull-aperture extended-depth oblique plane microscopy through dynamic remote focusing.
J Biomed Opt
March 2024
Politecnico di Milano, Dipartimento di Fisica, Milano, Italy.
Significance: The reprojection setup typical of oblique plane microscopy (OPM) limits the effective aperture of the imaging system, and therefore its efficiency and resolution. Large aperture system is only possible through the use of custom specialized optics. A full-aperture OPM made with off the shelf components would both improve the performance of the method and encourage its widespread adoption.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!