AI Article Synopsis

  • The intestinal microbiota plays a crucial role in individual health and immune response development.
  • A fecal transplantation study was conducted to see if the gut microbiota affects resistance to foodborne listeriosis in mice.
  • The results showed that transferring fecal matter between different mouse strains did not change their susceptibility or resistance to Listeria monocytogenes infection, indicating microbiota composition isn't a primary factor in this context.

Article Abstract

The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses.  In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota.  Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection.   Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice.  Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869484PMC
http://dx.doi.org/10.12688/f1000research.2-177.v1DOI Listing

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