AI Article Synopsis
- This study investigates the use of acoustic radiation force impulse (ARFI) imaging to visualize changes in tissue stiffness after radiofrequency ablation (RFA) in canine subjects.
- The main goals were to measure the displacements caused by ARFI in both ablated and unablated heart tissue and to evaluate the contrast and quality of ARFI images compared to standard echo images.
- Results showed that ARFI images had a higher accuracy in identifying lesion sites and produced better contrast and contrast-to-noise ratios than conventional imaging methods.
Article Abstract
We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify measured ARFI-induced displacements in RFA lesion and unablated myocardium and (2) calculate the lesion contrast (C) and contrast-to-noise ratio (CNR) in two-dimensional ARFI and conventional intracardiac echo images. In eight canine subjects, an ARFI imaging-electroanatomical mapping system was used to map right atrial ablation lesion sites and guide the acquisition of ARFI images at these sites before and after ablation. Readers of the ARFI images identified lesion sites with high sensitivity (90.2%) and specificity (94.3%) and the average measured ARFI-induced displacements were higher at unablated sites (11.23 ± 1.71 µm) than at ablated sites (6.06 ± 0.94 µm). The average lesion C (0.29 ± 0.33) and CNR (1.83 ± 1.75) were significantly higher for ARFI images than for spatially registered conventional B-mode images (C = -0.03 ± 0.28, CNR = 0.74 ± 0.68).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049337 | PMC |
| http://dx.doi.org/10.1177/0161734613519602 | DOI Listing |
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