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Acute Extrinsic Activation of the RANKL Pathway Decreases Wound Healing and Functional Recovery After Spinal Cord Injury in Mice.
Glia
January 2025
Burke Neurological Institute, White Plains, New York, USA.
Manipulating wound healing-associated signaling after SCI presents a promising avenue for increasing the recovery of function after injury. This study explores the potential of targeting molecular regulators of wound healing, initially identified in nonneural tissues, to enhance outcomes after SCI. Astrocytes, pivotal in central nervous system wound healing, play a crucial role in tissue remodeling and recovery.
View Article and Find Full Text PDFCellular Senescence Contributes to Colonic Barrier Integrity Impairment Induced by Toxoplasma gondii Infection.
Inflammation
January 2025
Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Toxoplasma gondii (T. gondii) induces gut barrier integrity impairment, which is crucial to the establishment of long-term infection in hosts. Cellular senescence is an imperative event that drives disease progression.
View Article and Find Full Text PDFSpin transport properties in a topological insulator sandwiched between two-dimensional magnetic layers.
Sci Rep
January 2025
Department of Applied Physics, School of Engineering Sciences, KTH Royal Institute of Technology, AlbaNova University Center, SE-10691, Stockholm, Sweden.
Non-trivial band topology along with magnetism leads to different novel quantum phases. When time-reversal symmetry is broken in three-dimensional topological insulators (TIs) through, e.g.
View Article and Find Full Text PDFQuantum transport under oscillatory drive with disordered amplitude.
J Phys Condens Matter
January 2025
Physics, Indian Institute of Science Education and Research Bhopal, Bypass Road Bhauri, Bhopal, 462066, INDIA.
We investigate the dynamics of non-interacting particles in a one-dimensional tight-binding chain in the presence of an electric field with random amplitude drawn from a Gaussian distribution, and explicitly focus on the nature of quantum transport. We derive an exact expression for the probability propagator and the mean-squared displacement in the clean limit and generalize it for the disordered case using the Liouville operator method. Our analysis reveals that in the presence a random static field, the system follows diffusive transport; however, an increase in the field strength causes a suppression in the transport and thus asymptotically leads towards localization.
View Article and Find Full Text PDFSubcytotoxic transepidermal delivery using low intensity cold atmospheric plasma.
Sci Rep
January 2025
Department of Dermatology, Chung-Ang University Hospital, 102, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea.
Cold atmospheric plasma (CAP) has been utilized in various medical devices using its oxidative nature. Recent studies have provided evidence that CAP can facilitate the delivery of large, hydrophilic molecules through the epidermis to the dermis. On the other hand, a new approach called low-intensity CAP (LICAP) has been developed, allowing the plasma level to be controlled within a subtoxic range, thereby demonstrating various biological benefits without tissue damage.
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