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http://dx.doi.org/10.1002/open.201200007 | DOI Listing |
ACS EST Air
January 2025
Environmental Engineering Program, University of Colorado Boulder, 1111 Engineering Drive, Boulder, Colorado 80309-0428, United States.
Quantifying changes in the properties of smoke aerosols under varying conditions is important for understanding the health and environmental impacts of exposure to smoke. Smoke composition, aerosol liquid water content, effective density (ρ), and other properties can change significantly as smoke travels through areas under different ambient conditions and over time. During this study, we measured changes in smoke composition and physical properties due to oxidative aging and exposure to humidity.
View Article and Find Full Text PDFOrg Lett
December 2024
Department of Chemistry, Indian Institute of Technology, Kharagpur, West Bengal 721302, India.
Development of metal-free conversion of naturally abundant phenols and anilines to the corresponding olefins remains a formidable challenge. The current state of the art relies on the TM-catalyzed Heck coupling of activated phenols (triflates, tosylates, and more) with the olefins. While these advancements are promising, the reaction suffers from branch vs linear selectivity and requires an expensive TM-ligand combination, hazardous organotin reagents, and very high reaction temperature.
View Article and Find Full Text PDFJ Org Chem
December 2024
Universitaet Potsdam, Institut fuer Chemie, Karl-Liebknecht-Straße 24-25, D-14476 Potsdam-Golm, Germany.
The synthesis of coumarin- and flavonoid-chalcone hybrids via Pd-catalyzed Heck-type coupling of arene diazonium salts and 8-allylcoumarins and -flavonoids is reported. The β-hydride elimination step proceeds with high regioselectivity if an OMOM-substituent is present at the position C7, adjacent to the allyl group. A selective allylic oxidation of the coupling products was accomplished using DDQ in the presence of silica to furnish the chalcones.
View Article and Find Full Text PDFChem Sci
December 2024
School of Chemical Engineering and Light Industry, Guangdong University of Technology No. 100 Waihuan Xi Road Guangzhou Higher Education Mega Center Guangzhou 510006 China
The oxidative Heck reaction of strongly coordinating heterocycles with internal olefins often led to elusive reactivity and regioselectivity. Herein, by judicious choice of X-type directing groups under Ru(ii) catalysis, we achieved the regioselective oxidative Heck reaction of strongly coordinating heterocycles with sterically demanding internal olefins. It was postulated that the "match/mismatch effect" of sterically demanding internal olefins as coupling partners and subsequent kinetically favoured Michael addition or oxidative aromatization act as driving forces to facilitate the desired reactivity and site-selectivity.
View Article and Find Full Text PDFRSC Med Chem
October 2024
Research Center on Fundamental and Applied Heterochemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University 11 Arany Janos str RO-400028 Cluj-Napoca Romania +40 264 593833.
New -substituted AB-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions, respectively. The free porphyrins were further used in the synthesis of new indium(iii) or zinc(ii) porphyrin complexes. All porphyrins exhibit red fluorescence emission in solution, a property that remains unimpaired following internalisation in ovarian A2780 cancer cells, as evidenced by fluorescence microscopy images.
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