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Case of severe bullous erythema including intertrigo-like eruptions with angioedema induced by pegylated liposomal doxorubicin.
J Dermatol
June 2019
Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Pegylated liposomal doxorubicin (PLD) is an anthracycline anticancer agent used in ovarian cancer and a form of doxorubicin enclosed in pegylated liposomes. There are only a few reports on intertrigo-like eruptions caused by PLD. We describe the first case of severe bullous erythema, including intertrigo-like eruptions with angioedema, induced by PLD in Japan.
View Article and Find Full Text PDFSkin toxicity in a patient with ovarian cancer treated with pegylated liposomal doxorubicin: A case report and review of the literature.
Oncol Lett
December 2016
Department of Chemotherapy, Medical University of Lodz, Copernicus Memorial Hospital, Lodz 93-513, Poland.
Pegylated liposomal doxorubicin (PLD) is a form of doxorubicin enclosed in pegylated liposomes. In contrast to conventional doxorubicin, PLD is characterized by a lower incidence of cardiotoxicity and myelosuppression. However, it induces specific mucocutaneous side effects, particularly palmar-plantar erythrodysesthesia (PPE).
View Article and Find Full Text PDFSerious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin.
An Bras Dermatol
January 2016
Sun Yat-sen University, Guangzhou, CN.
Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis.
View Article and Find Full Text PDFIntertrigo-like dermatitis with pegylated liposomal doxorubicin: diagnosis and management.
J Clin Oncol
November 2014
Dr Duchenne Hospital, Boulogne-sur-Mer, France.
Intertrigo-like eruption caused by pegylated liposomal doxorubicin (PLD).
Clin Transl Oncol
July 2009
Department of Medical Oncology, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain.
Pegylated liposomal doxorubicin (PLD) is a drug whose use is increasingly common. It has been associated with a lower rate of haematologic and cardiac side effects than its nonencapsulated form. However, mucocutaneous toxicity is quite frequent and can be severe.
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