A previously healthy 6-month-old boy presented to the pediatric dermatology clinic for evaluation of a persistent, pruritic eruption. This eruption involved the scalp, extremities, and inguinal creases and was intensely pruritic. The patient had been previously treated with multiple topical corticosteroids and antifungals, all with minimal improvement. He born at full term and was otherwise well and thriving. Review of systems was negative. Examination revealed erythematous to yellow scaly, greasy plaques, some with underlying purpuric papules in the frontal, temporal, and vertex of the scalp, post-auricular regions, and the conchae of both ears. There were also scattered papules and purpura noted in the inguinal creases, and hyperkeratotic yellow papules on the extensor extremities. He had no abnormal lymphadenopathy or hepatosplenomegaly. The remainder of his examination was normal. A diagnostic skin biopsy was performed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3928/00904481-20131223-10 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Increased ketone levels as a key magnetic resonance spectroscopic findings during acute exacerbation in -related Leigh syndrome.
Radiol Case Rep
December 2024
Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo, Chiba 276-8524, Japan.
Article Synopsis
- Short-chain enoyl-CoA hydratase is an important enzyme that helps break down certain fats and amino acids, and not having enough of it can lead to Leigh syndrome, a serious condition.
- A case was reported of a 6-month-old boy who showed symptoms like being sleepy and having trouble breathing, along with signs of severe ketosis, which means his body was producing too many ketones.
- Tests on his brain showed problems, and special genetic tests revealed he had changes in his genes that led to the enzyme deficiency; a diet low in valine might help manage this condition.
Anal canal duplication in a 6-month-old boy.
Asian J Surg
September 2024
Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, China. Electronic address:
Multimodal optical imaging of iris flocculi in three consecutive generations: a case report.
Front Med (Lausanne)
August 2024
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Multiple pigmented epithelial cysts at the edge of pupils, that is, iris flocculi, in both eyes, are rare ocular diseases. It has been demonstrated that this disease can be attributed to mutations in the smooth muscle α-actin 2 () gene, which mainly affects the function of smooth muscle cells (SMCs). SMCs are components of the iris, aorta, and several other systemic organs.
View Article and Find Full Text PDFProgressive familial intrahepatic cholestasis type 4: a case report.
J Med Case Rep
September 2024
Nile of Hope Hospital for Congenital Anomalies, Alexandria, Egypt.
Background: Progressive familial intrahepatic cholestasis is an autosomal recessive genetic disorder that manifests primarily with jaundice and pruritus and can progresses from persistent cholestasis to cirrhosis and late childhood liver failure. Classically, progressive familial intrahepatic cholestasis is classified into three subtypes: 1, 2, and 3 and results from a defect in a biliary protein responsible for bile formation and circulation in the liver. In the last decade and with the increased use of genetic testing, more types have been known.
View Article and Find Full Text PDFSerial 18 F-FDG PET/CT Revealing Mixed Histiocytosis in a Pediatric Patient.
Clin Nucl Med
October 2024
From the Department of Nuclear Medicine and PET, The Prince of Wales and Sydney Children's Hospitals, Randwick, Australia.
Article Synopsis
- A 6-month-old boy had soft tissue swelling and CT scans showed multiple bone lesions indicating a serious condition.
- PET/CT scans revealed hypermetabolic lesions in several areas, and a biopsy of one lesion confirmed it was Langerhans cell histiocytosis.
- After chemotherapy, further testing showed another lesion that was diagnosed as juvenile xanthogranuloma, highlighting a rare case of mixed histiocytosis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!