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High Antimicrobial Susceptibility of Cloacal Enterococci and from Free-Living Dalmatian and Great White Pelicans with Detection of Cefotaximase CTX-M-15 Producing ST69.
Antibiotics (Basel)
January 2025
SaBio Health and Biotechnology Research Group, Institute for Game and Wildlife Research (IREC), Ronda de Toledo 12, 13071 Ciudad Real, Spain.
In 2022, an outbreak of H5N1 highly pathogenic avian influenza (HPAI) killed 60% of the largest breeding colony of Dalmatian pelicans (DPs) in the world at Mikri Prespa Lake (Greece), prompting a multidisciplinary study on HPAI and other pathogens. This study determines the antimicrobial resistance rates of cloacal enterococci and in DPs. Fifty-two blood and cloacal swab samples were collected from 31 nestlings (20 DP/11 great white pelicans) hatched after the H5N1 outbreak at the Prespa colony and 21 subadult/adult DPs captured at a spring migration stopover.
View Article and Find Full Text PDFHigh prevalence of CTX-M-15 producing Shigella spp. isolated from patients with gastroenteritis in Northeast Iran.
Acta Microbiol Immunol Hung
December 2024
1Department of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Shigellosis, a diarrheal disease caused by Shigella species, is a significant public health concern, particularly in developing countries with inadequate sanitation systems. This study aimed to investigate the patterns of antibiotic resistance, ESBL and AmpC genes, integrons, and enterotoxin genes in Shigella species isolated from patients with gastroenteritis in Northeast Iran. This cross-sectional study was conducted between January 2017 and December 2019 at a tertiary care hospital in Northeast Iran.
View Article and Find Full Text PDFImpact of porin deficiency on the synergistic potential of colistin in combination with β-lactam/β-lactamase inhibitors against ESBL- and carbapenemase-producing .
Antimicrob Agents Chemother
November 2024
Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Combinations of colistin and β-lactam/β-lactamase inhibitors (BLBLIs) have shown synergy against β-lactamase-producing strains. However, data are limited and conflicting, potentially attributed to variations among the examined strains. This study investigated whether loss of porins OmpK35 and OmpK36 impacts the synergistic potential of colistin in combination with ceftazidime-avibactam or meropenem-avibactam against β-lactamase-producing .
View Article and Find Full Text PDFDistribution and Antimicrobial Susceptibility Pattern of CTX-M-type Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated in Chubu Region, Japan.
Jpn J Infect Dis
November 2024
Department of Clinical Infectious Diseases, Aichi Medical University Graduate School of Medicine, Japan.
The widespread prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli limits treatment options and is a worldwide problem. This study aimed to investigate the antimicrobial susceptibility and ESBL types of 204 strains of CTX-M-type ESBLsproducing E. coli isolated from 2011 to 2017 in the Chubu region of Japan and to identify factors correlated with susceptibility.
View Article and Find Full Text PDFGenomic Epidemiology of C2/H30Rx and C1-M27 Subclades of ST131 Isolates from Clinical Blood Samples in Hungary.
Antibiotics (Basel)
April 2024
Institute of Medical Microbiology, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Extended-spectrum β-lactamase-producing ST131 has become widespread worldwide. This study aims to characterize the virulome, resistome, and population structure of ST131 isolates from clinical blood samples in Hungary. A total of 30 C2/H30Rx and 33 C1-M27 ST131 isolates were selected for Illumina MiSeq sequencing and 30 isolates for MinION sequencing, followed by hybrid de novo assembly.
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