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http://dx.doi.org/10.1097/CCM.0000000000000086 | DOI Listing |
Research (Wash D C)
January 2025
Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Sepsis-associated encephalopathy (SAE) is a severe and frequent septic complication, characterized by neuronal damage as key pathological features. The astrocyte-microglia crosstalk in the central nervous system (CNS) plays important roles in various neurological diseases. However, how astrocytes interact with microglia to regulate neuronal injury in SAE is poorly defined.
View Article and Find Full Text PDFiScience
January 2025
Cognitive Neuroimaging Unit U992, CNRS, INSERM, CEA, DRF/Institut Joliot, Université Paris-Saclay, NeuroSpin Center, 91191 Gif/Yvette, France.
The need for attention to enable statistical learning is debated. Testing individuals with impaired consciousness offers valuable insight, but very few studies have been conducted due to the difficulties inherent in such studies. Here, we examined the ability of patients with varying levels of disorders of consciousness (DOC) to extract statistical regularities from an artificial language composed of randomly concatenated pseudowords by measuring frequency tagging in EEG.
View Article and Find Full Text PDFAlzheimers Dement (Amst)
January 2025
Weill Institute for Neurosciences, Department of Neurology, Memory and Aging Center University of California, San Francisco San Francisco California USA.
Introduction: Plasma amyloid beta/amyloid beta (Aβ/Aβ) and phosphorylated tau217 (p-tau217) identify individuals with primary Alzheimer's disease (AD). They may detect AD co-pathology in the setting of other primary neurodegenerative diseases, but this has not been systematically studied.
Methods: We compared the clinical, neuroimaging, and neuropathological associations of plasma Aβ/Aβ (mass spectrometry), p-tau217 (electrochemiluminescence), and neurofilament light ([NfL], single molecule array [Simoa]), as markers of AD co-pathology, in a sporadic frontotemporal dementia (FTD) cohort ( = 620).
Exp Ther Med
March 2025
Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region 830000, P.R. China.
Spinal cord injury (SCI) is a severe condition that often leads to permanent functional impairments. The current treatment options are limited and there is a need for more effective treatments. Human umbilical cord mesenchymal stem cells (hUCMSCs) have shown promise in promoting neuroregeneration and modulating immune response.
View Article and Find Full Text PDFFront Neurol
January 2025
Department of Neurosurgery, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Objective: The goal of this study was to develop a nomogram that integrates clinical data to predict the likelihood of severe postoperative peritumoral brain edema (PTBE) following the surgical removal of intracranial meningioma.
Method: We included 152 patients diagnosed with meningioma who were admitted to the Department of Neurosurgery at the Affiliated People's Hospital of Jiangsu University between January 2016 and March 2023. Clinical characteristics were collected from the hospital's medical record system.
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