Serratia marcescens is a common nosocomial infection but a rare cause of osteomyelitis and more so of vertebral osteomyelitis. Vertebral osteomyelitis caused by this organism has been reported in few studies. We report a case of S. marcescens vertebral discitis and osteomyelitis affecting multiple non-contiguous vertebras. Although Staphylococcus aureus is the most common cause of vertebral osteomyelitis, rare causes, such as S. marcescens, need to be considered, especially when risk factors such as intravenous heroin use, post-spinal surgery and immunosuppression are present. Therefore, blood culture and where necessary biopsy of the infected region should be undertaken to establish the causative organism and determine appropriate antibiotic susceptibility. Prompt diagnosis of S. marcescens vertebral osteomyelitis followed by the appropriate treatment can achieve successful outcomes.
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http://dx.doi.org/10.3109/14397595.2013.874754 | DOI Listing |
Spine (Phila Pa 1976)
December 2024
University of Missouri-Kansas City School of Medicine, 2411 Holmes St, Kansas City, MO 64108.
Study Design: Systematic Review and Network-Meta-analysis.
Purpose: This study aimed to systematically review the literature on management of primary osteomyelitis discitis and perform a network meta-analysis comparing the efficacy of different antibiotic treatment durations.
Background: Primary osteomyelitis discitis is a challenging condition with varying management strategies.
Int J Infect Dis
December 2024
Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Objectives: The aims of this study were 1) to investigate seasonal epidemiological variations of pyogenic spondylodiscitis, including Methicillin-resistant Staphylococcus aureus (MRSA) infection, in Japan, and 2) to evaluate associated inpatient outcomes.
Methods: We performed a retrospective nationwide study using data from the Japanese Diagnosis Procedure Combination (DPC) inpatient database, covering the period from 2010 to 2022. The parameters assessed were seasonal incidence, demographic characteristics, inpatient mortality, complications, and medical costs.
AJNR Am J Neuroradiol
December 2024
From the Department of Radiology (DGM., MVS., GMS., REG., JSR., TJR.) Mayo Clinic, Phoenix, AZ, USA; Department of Radiology (FED.), Mayo Clinic, Rochester, MN, USA. Department of Radiology (EHM.), Mayo Clinic, Jacksonville, FL, USA.
Background And Purpose: Studies show a modest yield for image-guided biopsy of suspected vertebral osteomyelitis-discitis. Many studies evaluate factors to improve diagnostic yield, and few studies assess how biopsy results impact clinical management. We aim to evaluate the impact of biopsy results on clinical management in suspected vertebral osteomyelitis-discitis.
View Article and Find Full Text PDFInfection
December 2024
Department I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
Purpose: Patients with vertebral osteomyelitis (VO) and comorbidities, notably chronic kidney disease (CKD), are at risk of early mortality. The aim of this study was to compare characteristics and outcomes of VO patients with an underlying malignancy (ONCO) to VO patients with CKD and VO patients without comorbidities (CONTROL).
Methods: We performed a retrospective analysis of data which was prospectively collected between 2008 and 2020.
BMC Infect Dis
December 2024
108 Military Central Hospital, Vietnamese - German Center for Medical Research (VG-CARE), N 1, Tran Hung Dao Str., Hai Ba Trung Dist, Hanoi, 1000, Vietnam.
Citrobacter youngae (C. youngae) was first described in 1993, and data suggesting that human diseases caused by this bacterium remain scarce. Reports on C.
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