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| http://dx.doi.org/10.1016/j.mjafi.2011.11.007 | DOI Listing |
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The use of a methylene blue and glyceryl trinitrate-based cream for the treatment of chronic anal fissures: a phase II randomized pilot trial from a referral coloproctological unit.
Tech Coloproctol
January 2025
Department of Precision and Regenerative Medicine and Jonic Area (DiMePRe-J), Section of Surgery, General Surgery Unit - Hospital University of Bari, Piazza Giulio Cesare 11, 70124, Bari, SE, Italy.
Background: Chronic anal fissures (CAFs) are the second most common anorectal disease. Non-surgical treatment includes several options with controversial efficacy. The aim of this study was to evaluate the efficacy and safety of a new ointment based on methylene blue in addition to glyceryl trinitrate.
View Article and Find Full Text PDFA Biokinetic Approach in Primary Knee Osteoarthritis Prevention and Management - Exploring Movement Profiles and Kinetic Chain Interactions: Current Concepts.
J ISAKOS
December 2024
Instituto Brasil de Tecnologias da Saúde (IBTS), Department of Research in Biomechanics, Rio de Janeiro, RJ, Brazil; Universidade Federal de São Paulo, Department of Diagnostic Imaging, São Paulo, SP, Brazil. Electronic address:
Knee osteoarthritis (OA) is a chronic disease characterized by increasing prevalence and significant physical, psychological, and economic burdens. Despite extensive research, the definition, risk factors, and effective cost-efficient treatments for knee OA remain unclear. This article aims to revisit primary knee OA, understanding its etiology, and focusing on prevention and individualized non-operative treatment modalities.
View Article and Find Full Text PDFManagement of uncomplicated acute appendicitis: a protocol for systematic review and network meta-analysis of randomised-controlled trials.
BMJ Open
December 2024
Department of Emergency Medicine, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, People's Republic of China
Objectives: While multiple studies have shown the safety and efficacy of non-operative management, appendectomy remains the standard treatment for uncomplicated acute appendicitis (UAA). This study presents a protocol for a meta-analysis comparing antibiotic therapy, endoscopic retrograde appendicitis therapy (ERAT) and appendectomy in patients with UAA.
Methods And Analysis: We will conduct a systematic search of several databases, including PubMed, Web of Science, Embase, the China National Knowledge Infrastructure and the Cochrane Library.
Comparing total medical costs of surgical treatment versus nonoperative care for femoral neck fractures among Alzheimer's disease patients: A retrospective cohort study.
Geriatr Nurs
December 2024
Department of Management, Policy and Community Health, School of Public Health, The University of Texas Health Science Center at Houston, Houston 77030, Texas, United States. Electronic address:
Objectives: To compare the total medical costs associated with operative versus non-operative medical procedures for femoral neck fractures in older adults with Alzheimer's disease (AD).
Methods: This retrospective cohort study examined 4,157 Optum beneficiaries diagnosed with AD who filed an initial claim for femoral neck fracture between January 1, 2012, and December 31, 2017. Generalized linear regression with Gamma log link function was performed to evaluate total medical costs between surgical treatment and non-operative care while controlling for covariates.
Adolescent Idiopathic Scoliosis: Advances in Diagnosis and Management.
Curr Rev Musculoskelet Med
December 2024
Wake Forest School of Medicine, Department of Orthopaedic Surgery, 1 Medical Center Blvd, Winston Salem, NC, 27103, USA.
Purpose Of Review: Adolescent idiopathic scoliosis (AIS) is a disabling spinal pathology, with a significant morbidity if left untreated. This review investigates the recent advances in the diagnosis and management of AIS.
Recent Findings: Low radiation techniques have become a paramount focus in the management of patient's with AIS.
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